Difference between revisions of "Melanocytic lesions"

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→‎Clark nevus: rename to dysplastic again
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(→‎Clark nevus: rename to dysplastic again)
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**In acral sites the criteria are relaxed, i.e. this is considered benign for this site.
**In acral sites the criteria are relaxed, i.e. this is considered benign for this site.


==Clark nevus==
==Dysplastic melanocytic nevus==
*[[AKA]] ''dysplastic nevus''.
*[[AKA]] ''dysplastic nevus''.
*[[AKA]] ''dysplastic melanocytic nevus''.
*[[AKA]] ''Clark nevus''.


===General===
===General===
*Benign.
*Benign.
*Clark nevi are considered a risk factor for [[malignant melanoma|melanoma]] and may be a precursor of melanoma, as the name ''dysplastic nevus'' suggests.<ref name=pmid21308311>{{Cite journal  | last1 = Rezze | first1 = GG. | last2 = Leon | first2 = A. | last3 = Duprat | first3 = J. | title = Dysplastic nevus (atypical nevus). | journal = An Bras Dermatol | volume = 85 | issue = 6 | pages = 863-71 | month = Dec | year = 2010 | doi =  | PMID = 21308311 }}</ref>  
*Dysplastic nevi are considered a risk factor for [[malignant melanoma|melanoma]] and may be a precursor of melanoma, as the name ''dysplastic nevus'' suggests.<ref name=pmid21308311>{{Cite journal  | last1 = Rezze | first1 = GG. | last2 = Leon | first2 = A. | last3 = Duprat | first3 = J. | title = Dysplastic nevus (atypical nevus). | journal = An Bras Dermatol | volume = 85 | issue = 6 | pages = 863-71 | month = Dec | year = 2010 | doi =  | PMID = 21308311 }}</ref>  
**Most melanoma cases do not have evidence of a pre-existing (dysplastic) nevus.<ref name=pmid21715047>{{Cite journal  | last1 = Longo | first1 = C. | last2 = Rito | first2 = C. | last3 = Beretti | first3 = F. | last4 = Cesinaro | first4 = AM. | last5 = Piñeiro-Maceira | first5 = J. | last6 = Seidenari | first6 = S. | last7 = Pellacani | first7 = G. | title = De novo melanoma and melanoma arising from pre-existing nevus: in vivo morphologic differences as evaluated by confocal microscopy. | journal = J Am Acad Dermatol | volume = 65 | issue = 3 | pages = 604-14 | month = Sep | year = 2011 | doi = 10.1016/j.jaad.2010.10.035 | PMID = 21715047 }}</ref>
**Most melanoma cases do not have evidence of a pre-existing (dysplastic) nevus.<ref name=pmid21715047>{{Cite journal  | last1 = Longo | first1 = C. | last2 = Rito | first2 = C. | last3 = Beretti | first3 = F. | last4 = Cesinaro | first4 = AM. | last5 = Piñeiro-Maceira | first5 = J. | last6 = Seidenari | first6 = S. | last7 = Pellacani | first7 = G. | title = De novo melanoma and melanoma arising from pre-existing nevus: in vivo morphologic differences as evaluated by confocal microscopy. | journal = J Am Acad Dermatol | volume = 65 | issue = 3 | pages = 604-14 | month = Sep | year = 2011 | doi = 10.1016/j.jaad.2010.10.035 | PMID = 21715047 }}</ref>
*Large numbers of these nevi (10-100) are seen in ''dysplastic nevus syndrome''.<ref name=omim155600>{{OMIM|155600}}</ref>  
*Large numbers of these nevi (10-100) are seen in ''dysplastic nevus syndrome''.<ref name=omim155600>{{OMIM|155600}}</ref>  
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