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Difference between revisions of "Neuropathology tumours"
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→Pleomorphic xanthoastrocytoma
m (→IHC: w) |
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*Classically in the temporal lobe in children and young adults. | *Classically in the temporal lobe in children and young adults. | ||
*Associated with seizures. | *Associated with seizures. | ||
*Moderately aggressive (WHO Grade II).<ref name=pmid11465399>{{Cite journal | last1 = Fouladi | first1 = M. | last2 = Jenkins | first2 = J. | last3 = Burger | first3 = P. | last4 = Langston | first4 = J. | last5 = Merchant | first5 = T. | last6 = Heideman | first6 = R. | last7 = Thompson | first7 = S. | last8 = Sanford | first8 = A. | last9 = Kun | first9 = L. | title = Pleomorphic xanthoastrocytoma: favorable outcome after complete surgical resection. | journal = Neuro Oncol | volume = 3 | issue = 3 | pages = 184-92 | month = Jul | year = 2001 | doi = | PMID = 11465399 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920613/pdf/11465399.pdf}}</ref> | |||
===Gross=== | |||
*Temporal lobe. | |||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_PBoD8_1333>{{Ref PBoD8|1333}}</ref> | Features:<ref name=Ref_PBoD8_1333>{{Ref PBoD8|1333}}</ref> | ||
*Marked nuclear atypia. | *Marked nuclear atypia. | ||
*Eosinophilic granular bodies - very common.<ref name=pmid11465399/> | |||
*Inflammation (chronic). | *Inflammation (chronic). | ||
Notes: | Notes: | ||
*No mitoses. | *No mitoses. | ||
*No necrosis. | *No [[necrosis]]. | ||
Images: | Images: | ||