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Difference between revisions of "Pulmonary cytopathology"
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**Chromatin clumping. | **Chromatin clumping. | ||
**Marked nuclear size variation. | **Marked nuclear size variation. | ||
*Nuclear moulding - most useful for distinguishing from NSCLC<ref>{{Cite journal | last1 = Sturgis | first1 = CD. | last2 = Nassar | first2 = DL. | last3 = D'Antonio | first3 = JA. | last4 = Raab | first4 = SS. | title = Cytologic features useful for distinguishing small cell from non-small cell carcinoma in bronchial brush and wash specimens. | journal = Am J Clin Pathol | volume = 114 | issue = 2 | pages = 197-202 | month = Aug | year = 2000 | doi = 10.1309/8MQG-6XEK-3X9L-A9XU | PMID = 10941334 |url=http://ajcp.ascpjournals.org/content/114/2/197.full.pdf }}</ref><ref>URL: [http://onlinelibrary.wiley.com/doi/10.1002/dc.10297/abstract http://onlinelibrary.wiley.com/doi/10.1002/dc.10297/abstract]. Accessed on: 31 May 2011.</ref> - '''key feature'''. | *Nuclear moulding - most useful for distinguishing from NSCLC<ref name=pmid10941334>{{Cite journal | last1 = Sturgis | first1 = CD. | last2 = Nassar | first2 = DL. | last3 = D'Antonio | first3 = JA. | last4 = Raab | first4 = SS. | title = Cytologic features useful for distinguishing small cell from non-small cell carcinoma in bronchial brush and wash specimens. | journal = Am J Clin Pathol | volume = 114 | issue = 2 | pages = 197-202 | month = Aug | year = 2000 | doi = 10.1309/8MQG-6XEK-3X9L-A9XU | PMID = 10941334 |url=http://ajcp.ascpjournals.org/content/114/2/197.full.pdf }}</ref><ref>URL: [http://onlinelibrary.wiley.com/doi/10.1002/dc.10297/abstract http://onlinelibrary.wiley.com/doi/10.1002/dc.10297/abstract]. Accessed on: 31 May 2011.</ref> - '''key feature'''. | ||
*Stippled chromatin - '''key feature'''. | *Stippled chromatin - '''key feature'''. | ||
*Scant cytoplasm - so scant it often near impossible to see - '''important feature'''. | *Scant cytoplasm - so scant it often near impossible to see - '''important feature'''. | ||
*Small cells ~ 2x RBC. | *Small cells ~ 2x RBC. | ||
*Bare nuclei common - very useful if present. | *Bare nuclei common - very useful if present. | ||
*Necrosis - '''essential''. | |||
**Cell fragmentation - smeared gray background (Pap stain), fragmented nuclei. | |||
Notes: | Notes: | ||