Difference between revisions of "Tumour regression"

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==Sporadic tumour regression==
==Sporadic tumour regression==
Well-known:
*[[Testis|Testicular]] [[germ cell tumours]].<ref name=pmid16819328>{{Cite journal  | last1 = Balzer | first1 = BL. | last2 = Ulbright | first2 = TM. | title = Spontaneous regression of testicular germ cell tumors: an analysis of 42 cases. | journal = Am J Surg Pathol | volume = 30 | issue = 7 | pages = 858-65 | month = Jul | year = 2006 | doi = 10.1097/01.pas.0000209831.24230.56 | PMID = 16819328 }}</ref>
*[[Testis|Testicular]] [[germ cell tumours]].<ref name=pmid16819328>{{Cite journal  | last1 = Balzer | first1 = BL. | last2 = Ulbright | first2 = TM. | title = Spontaneous regression of testicular germ cell tumors: an analysis of 42 cases. | journal = Am J Surg Pathol | volume = 30 | issue = 7 | pages = 858-65 | month = Jul | year = 2006 | doi = 10.1097/01.pas.0000209831.24230.56 | PMID = 16819328 }}</ref>
*[[Malignant melanoma]].
*[[Malignant melanoma]].
Line 10: Line 11:
*+/-Fibrosis.
*+/-Fibrosis.
*+/-Mucin.
*+/-Mucin.
*+/-Inflammation.
===Grading of tumour regression===
There is a three tiered regression grading system by Ryan ''et al''..<ref name=pmid16045774>{{Cite journal  | last1 = Ryan | first1 = R. | last2 = Gibbons | first2 = D. | last3 = Hyland | first3 = JM. | last4 = Treanor | first4 = D. | last5 = White | first5 = A. | last6 = Mulcahy | first6 = HE. | last7 = O'Donoghue | first7 = DP. | last8 = Moriarty | first8 = M. | last9 = Fennelly | first9 = D. | title = Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. | journal = Histopathology | volume = 47 | issue = 2 | pages = 141-6 | month = Aug | year = 2005 | doi = 10.1111/j.1365-2559.2005.02176.x | PMID = 16045774 }}</ref>


==References==
==References==
{{Reflist|1}}
{{Reflist|2}}


[[Category:Basics]]
[[Category:Basics]]

Revision as of 00:52, 7 April 2012

Tumour regression can occur as a consequence of treatment or sporadically.

Sporadic tumour regression

Well-known:

Microscopic

Features:

  • +/-Fibrosis.
  • +/-Mucin.
  • +/-Inflammation.

Grading of tumour regression

There is a three tiered regression grading system by Ryan et al..[2]

References

  1. Balzer, BL.; Ulbright, TM. (Jul 2006). "Spontaneous regression of testicular germ cell tumors: an analysis of 42 cases.". Am J Surg Pathol 30 (7): 858-65. doi:10.1097/01.pas.0000209831.24230.56. PMID 16819328.
  2. Ryan, R.; Gibbons, D.; Hyland, JM.; Treanor, D.; White, A.; Mulcahy, HE.; O'Donoghue, DP.; Moriarty, M. et al. (Aug 2005). "Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer.". Histopathology 47 (2): 141-6. doi:10.1111/j.1365-2559.2005.02176.x. PMID 16045774.