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Difference between revisions of "Neuropathology tumours"
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→Lhermitte-Duclos disease: +add alt. name
(→Lhermitte-Duclos disease: +add alt. name) |
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==Lhermitte-Duclos disease== | ==Lhermitte-Duclos disease== | ||
*Abbreviated ''LDD''. | *Abbreviated ''LDD''. | ||
*[[AKA]] ''dysplastic cerebellar gangliocytoma''.<ref name=pmid20060133>{{Cite journal | last1 = Yağci-Küpeli | first1 = B. | last2 = Oguz | first2 = KK. | last3 = Bilen | first3 = MA. | last4 = Yalçin | first4 = B. | last5 = Akalan | first5 = N. | last6 = Büyükpamukçu | first6 = M. | title = An unusual cause of posterior fossa mass: Lhermitte-Duclos disease. | journal = J Neurol Sci | volume = 290 | issue = 1-2 | pages = 138-41 | month = Mar | year = 2010 | doi = 10.1016/j.jns.2009.12.010 | PMID = 20060133 }}</ref> | |||
===General=== | ===General=== | ||
*Cerebellar lesion. | *Cerebellar lesion. | ||
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref>URL: [http://path.upmc.edu/cases/case472.html http://path.upmc.edu/cases/case472.html]. Accessed on: 21 January 2012.</ref> | Features:<ref>URL: [http://path.upmc.edu/cases/case472.html http://path.upmc.edu/cases/case472.html]. Accessed on: 21 January 2012.</ref> | ||
*The outer (molecular) layer has increased cellularity. | |||
*Purkinje cells absent.<ref name=pmid20060133/> | |||
*Large (polygonal) cells with round nuclei and prominent nucleoli in the inner (granular) layer - '''key feature'''. | *Large (polygonal) cells with round nuclei and prominent nucleoli in the inner (granular) layer - '''key feature'''. | ||
*+/-Microcalcifications. | *+/-Microcalcifications. | ||