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| '''Syncytiotrophoblast''' | | '''Syncytiotrophoblast''' | ||
| '''Villous intermediate<br>trophoblast''' | | '''Villous intermediate<br>trophoblast''' | ||
| ''' | | '''Implantation site<br>intermediate trophoblast''' | ||
| '''Chorionic-type<br>intermediate trophoblast''' | | '''Chorionic-type<br>intermediate trophoblast''' | ||
|- | |- | ||
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| Cytoplasm | | Cytoplasm | ||
| minimal, clear to granular | | minimal, clear to granular | ||
| abundant, vacuolated | | abundant, vacuolated, basophilic (???) | ||
| abundant & eosinophilic to clear | | abundant & eosinophilic to clear | ||
| abundant & eosinophilic | | abundant & eosinophilic | ||
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|- | |- | ||
| IHC | | IHC | ||
| beta-hCG ??? | | beta-hCG -ve (???), p63 +ve<ref name=pmid19188816>{{Cite journal | last1 = Zhang | first1 = HJ. | last2 = Xue | first2 = WC. | last3 = Siu | first3 = MK. | last4 = Liao | first4 = XY. | last5 = Ngan | first5 = HY. | last6 = Cheung | first6 = AN. | title = P63 expression in gestational trophoblastic disease: correlation with proliferation and apoptotic dynamics. | journal = Int J Gynecol Pathol | volume = 28 | issue = 2 | pages = 172-8 | month = Mar | year = 2009 | doi = 10.1097/PGP.0b013e318189555b | PMID = 19188816 }}</ref> | ||
| beta-hCG | | beta-hCG +ve | ||
| | | p63 +ve,<ref name=pmid19188816/> PLAP +ve | ||
| inhibin+, hPL+, beta-hCG-<ref name=pmid1694585>{{cite journal |author=Yeh IT, O'Connor DM, Kurman RJ |title=Intermediate trophoblast: further immunocytochemical characterization |journal=Mod. Pathol. |volume=3 |issue=3 |pages=282–7 |year=1990 |month=May |pmid=1694585 |doi= |url=}}</ref> CD146+,<ref name=pmid10451481>{{Cite journal | last1 = Shih | first1 = IM. | title = The role of CD146 (Mel-CAM) in biology and pathology. | journal = J Pathol | volume = 189 | issue = 1 | pages = 4-11 | month = Sep | year = 1999 | doi = 10.1002/(SICI)1096-9896(199909)189:14::AID-PATH3323.0.CO;2-P | PMID = 10451481 }}</ref> p63- | | inhibin +ve, hPL +ve, beta-hCG -ve<ref name=pmid1694585>{{cite journal |author=Yeh IT, O'Connor DM, Kurman RJ |title=Intermediate trophoblast: further immunocytochemical characterization |journal=Mod. Pathol. |volume=3 |issue=3 |pages=282–7 |year=1990 |month=May |pmid=1694585 |doi= |url=}}</ref> CD146+,<ref name=pmid10451481>{{Cite journal | last1 = Shih | first1 = IM. | title = The role of CD146 (Mel-CAM) in biology and pathology. | journal = J Pathol | volume = 189 | issue = 1 | pages = 4-11 | month = Sep | year = 1999 | doi = 10.1002/(SICI)1096-9896(199909)189:14::AID-PATH3323.0.CO;2-P | PMID = 10451481 }}</ref> p63 -ve | ||
| hPL+/-, p63+, CD146- | | hPL +ve/-ve, p63 +ve, CD146 -ve | ||
|- | |- | ||
| Image | | Image |
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