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Difference between revisions of "Neuroendocrine neoplasms"
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→Carcinoid syndrome
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=Carcinoid syndrome= | =Carcinoid syndrome= | ||
==Pathophysiology== | ===Pathophysiology=== | ||
*Neuroendocrine tumour -> hormone secretion (5-hydroxytryptamine + others).<ref name=pmid19444261>{{Cite journal | last1 = Druce | first1 = M. | last2 = Rockall | first2 = A. | last3 = Grossman | first3 = AB. | title = Fibrosis and carcinoid syndrome: from causation to future therapy. | journal = Nat Rev Endocrinol | volume = 5 | issue = 5 | pages = 276-83 | month = May | year = 2009 | doi = 10.1038/nrendo.2009.51 | PMID = 19444261 }}</ref> | *Neuroendocrine tumour -> hormone secretion (5-hydroxytryptamine + others).<ref name=pmid19444261>{{Cite journal | last1 = Druce | first1 = M. | last2 = Rockall | first2 = A. | last3 = Grossman | first3 = AB. | title = Fibrosis and carcinoid syndrome: from causation to future therapy. | journal = Nat Rev Endocrinol | volume = 5 | issue = 5 | pages = 276-83 | month = May | year = 2009 | doi = 10.1038/nrendo.2009.51 | PMID = 19444261 }}</ref> | ||
==Clinical== | ===Clinical=== | ||
Features:<ref name=pmid19444261/> | Features:<ref name=pmid19444261/> | ||
*Diarrhea, flushing and wheezing. | *Diarrhea, flushing and wheezing. | ||
==Pathologic findings== | ===Pathologic findings=== | ||
Classic pathologic finding:<ref name=pmid19444261/> | Classic pathologic finding:<ref name=pmid19444261/> | ||
*Fibrosis of cardiac valves (tricuspid and pulmonary). | *Fibrosis of cardiac valves (tricuspid and pulmonary). | ||