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Difference between revisions of "Neuroendocrine neoplasms"
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Subtypes:<ref name=pmid21601112>{{Cite journal | last1 = Scoazec | first1 = JY. | last2 = Couvelard | first2 = A. | title = [The new WHO classification of digestive neuroendocrine tumors]. | journal = Ann Pathol | volume = 31 | issue = 2 | pages = 88-92 | month = Apr | year = 2011 | doi = 10.1016/j.annpat.2011.01.001 | PMID = 21601112 }}</ref> | Subtypes:<ref name=pmid21601112>{{Cite journal | last1 = Scoazec | first1 = JY. | last2 = Couvelard | first2 = A. | title = [The new WHO classification of digestive neuroendocrine tumors]. | journal = Ann Pathol | volume = 31 | issue = 2 | pages = 88-92 | month = Apr | year = 2011 | doi = 10.1016/j.annpat.2011.01.001 | PMID = 21601112 }}</ref> | ||
#Neuroendocrine tumour G1. | #Neuroendocrine tumour G1. | ||
#Neuroendocrine | #Neuroendocrine tumour G2. | ||
#Neuroendocrine carcinoma, small cell type. | #Neuroendocrine carcinoma, small cell type. | ||
#Neuroendocrine carcinoma, large cell type. | #Neuroendocrine carcinoma, large cell type. | ||
#Mixed adenoneuroendocrine carcinoma. | #Mixed adenoneuroendocrine carcinoma. | ||
====Grading==== | |||
Grading of NETs:<ref name=pmid21344263>{{Cite journal | last1 = Volante | first1 = M. | last2 = Righi | first2 = L. | last3 = Berruti | first3 = A. | last4 = Rindi | first4 = G. | last5 = Papotti | first5 = M. | title = The pathological diagnosis of neuroendocrine tumors: common questions and tentative answers. | journal = Virchows Arch | volume = 458 | issue = 4 | pages = 393-402 | month = Apr | year = 2011 | doi = 10.1007/s00428-011-1060-7 | PMID = 21344263 }}</ref> | |||
*G1: < 2 mitoses/2 mm^2 ''or'' < 3% Ki-67. | |||
*G2: > 2 mitoses/2 mm^2 ''or'' > 3% Ki-67 '''and''' < 20 mitoses/2 mm^2 ''or'' < 20% Ki-67. | |||
*G3: > 20 mitoses/2 mm^2 ''or'' > 20% Ki-67. | |||
Notes: | |||
*Neuroendocrine carcinomas are G3 by definition. | |||
<br> | <br> | ||