Thrombotic thrombocytopenic purpura: Difference between revisions
Jump to navigation
Jump to search
m formating |
→See also: +HUS |
||
| (7 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
'''Thrombotic thrombocytopenic purpura''' is a type of [[thrombotic microangiopathy]]. | '''Thrombotic thrombocytopenic purpura''', abbreviated '''TTP''', is a type of [[thrombotic microangiopathy]]. | ||
==Classic pentad== | ==Classic pentad== | ||
It was classically described as the pentad of:<ref>{{Ref PBoD8|669}}</ref> | It was classically described as the pentad of:<ref name=Ref_PBoD8_669>{{Ref PBoD8|669}}</ref> | ||
#Fever. | #Fever. | ||
#Thrombocytopenia. | #Thrombocytopenia. | ||
#Microangiopathic hemolytic anemia. | #Microangiopathic hemolytic [[anemia]]. | ||
#*Usu. with schistocytes (fragmented [[RBC]]s).<ref>{{Ref Klatt|65}}</ref> | |||
#Transient neurologic symptoms. | #Transient neurologic symptoms. | ||
#Renal failure. | #Renal failure. | ||
===Mnemonic=== | ===Mnemonic=== | ||
''HUS/TTP is a CRAFTY syndrome'':<ref>URL: [http://www.valuemd.com/mnemonics2.php http://www.valuemd.com/mnemonics2.php]. Accessed on: 8 November 2010.</ref> | ''[[HUS]]/TTP is a CRAFTY syndrome'':<ref>URL: [http://www.valuemd.com/mnemonics2.php http://www.valuemd.com/mnemonics2.php]. Accessed on: 8 November 2010.</ref> | ||
*'''C'''NS symptoms. | *'''C'''NS symptoms. | ||
*'''R'''enal failure. | *'''R'''enal failure. | ||
| Line 16: | Line 17: | ||
*'''F'''ever. | *'''F'''ever. | ||
*'''T'''hrombocytopenia. | *'''T'''hrombocytopenia. | ||
*'''Y''' - no one knows "Y" it occurs. | *'''Y''' - no one knows "Y" it occurs. | ||
==Etiology== | |||
Deficiency of plasma enzyme ''ADAMTS13'' which may be:<ref name=Ref_PBoD8_669>{{Ref PBoD8|669}}</ref> | |||
*Inherited. | |||
*Acquired (autoantibodies). | |||
==See also== | ==See also== | ||
*[[Vasculitides]]. | *[[Vasculitides]]. | ||
*[[Hemolytic uremic syndrome]]. | |||
*[[Medical renal diseases]]. | *[[Medical renal diseases]]. | ||
*[[Anemia]]. | |||
==References== | ==References== | ||
| Line 26: | Line 34: | ||
[[Category:Cardiovascular pathology]] | [[Category:Cardiovascular pathology]] | ||
[[Category:Diagnosis]] | |||