Difference between revisions of "Lung tumours"

Lung tumours (view source)

1,109 bytes added , 15:56, 11 February 2012

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 =Malignant potential=
+==Atypical alveolar hyperplasia==
+*Abbreviated ''AAH''.
+===General===
+*Generally considered the precursor lesion to ''adenocarcinoma in situ''.<ref name=pmid17618248>{{Cite journal  | last1 = Sakuma | first1 = Y. | last2 = Matsukuma | first2 = S. | last3 = Yoshihara | first3 = M. | last4 = Nakamura | first4 = Y. | last5 = Nakayama | first5 = H. | last6 = Kameda | first6 = Y. | last7 = Tsuchiya | first7 = E. | last8 = Miyagi | first8 = Y. | title = Epidermal growth factor receptor gene mutations in atypical adenomatous hyperplasias of the lung. | journal = Mod Pathol | volume = 20 | issue = 9 | pages = 967-73 | month = Sep | year = 2007 | doi = 10.1038/modpathol.3800929 | PMID = 17618248 }}</ref>
+===Microscopic===
+Features:<ref name=Ref_WMSP114>{{Ref WMSP|114}}</ref>
+*Enlarged alveolar lining cells with:
+**Hobnail morphology - free (luminal) surface area > attached/basal surface area.
+**Hyperchromasia.
+*Limited extent:
+**<5 mm.
+DDx:
+*Adenocarcinoma in situ.
+Image:
+*[http://www.nature.com/modpathol/journal/v20/n9/fig_tab/3800929f1.html#figure-title AAH (nature.com)].<ref name=pmid17618248/>
 ==Atypical carcinoid lung tumour==
 *[[AKA]] ''carcinoid tumour of the lung''.