Difference between revisions of "Ovary"
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(→Benign mesothelial inclusion cyst: +pregnancy luteoma) |
(→Pregnancy luteoma: more) |
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*Benign. | *Benign. | ||
*Regress after pregnancy; thus, conservative management.<ref name=pmid21144088>{{Cite journal | last1 = Masarie | first1 = K. | last2 = Katz | first2 = V. | last3 = Balderston | first3 = K. | title = Pregnancy luteomas: clinical presentations and management strategies. | journal = Obstet Gynecol Surv | volume = 65 | issue = 9 | pages = 575-82 | month = Sep | year = 2010 | doi = 10.1097/OGX.0b013e3181f8c41d | PMID = 21144088 }}</ref> | *Regress after pregnancy; thus, conservative management.<ref name=pmid21144088>{{Cite journal | last1 = Masarie | first1 = K. | last2 = Katz | first2 = V. | last3 = Balderston | first3 = K. | title = Pregnancy luteomas: clinical presentations and management strategies. | journal = Obstet Gynecol Surv | volume = 65 | issue = 9 | pages = 575-82 | month = Sep | year = 2010 | doi = 10.1097/OGX.0b013e3181f8c41d | PMID = 21144088 }}</ref> | ||
Clinical: | |||
*Increased serum testosterone.<ref name=pmid15782020>{{Cite journal | last1 = Kao | first1 = HW. | last2 = Wu | first2 = CJ. | last3 = Chung | first3 = KT. | last4 = Wang | first4 = SR. | last5 = Chen | first5 = CY. | title = MR imaging of pregnancy luteoma: a case report and correlation with the clinical features. | journal = Korean J Radiol | volume = 6 | issue = 1 | pages = 44-6 | month = | year = | doi = | PMID = 15782020 }}</ref> | |||
===Microscopic=== | ===Microscopic=== | ||
Revision as of 02:25, 31 January 2012
The ovary has a wealth of pathology. It has benign tumours and malignant ones.
Normal
- Corpora albicans - pale/white body with lobulated contour.
- Ovarian follicles.
- Stroma - hyperchromatic - spindle morphology, whorling.
- If the cells have a round morphology... think about endometriosis.
Micrograph
Cysts
General:
- Very common.
Most common:
- Serous cystadenoma.
- Usually uniloculated.
- Morphology: ciliated, columnar.
- Mucinous cystadenoma.
- Usually multiloculated.[1]
- Memory device: multiloculated = mucinous.
- Usually multiloculated.[1]
- Endometrioma (see endometriosis).
- Simple cyst.
- Cancerous cyst (see ovarian cancer).
Notes
- Epithelium is often lost in processing - may make interpretation challenging
- Ovarian surface epithelium (previously call germinal epithelium) - covers the ovary
Ovarian surface vs. mesothelium:
- Image: ovarian surface epithelium - endojournals.org.
- Image: mesothelium - internetattitude.com.
Endometriosis
Main article: Endometriosis
Ovarian tumours
Main article: Ovarian tumours
For a very brief overview of gynecologic tumours see: Gynecologic pathology.
Benign mesothelial inclusion cyst
Epidemiology
- Assoc. with previous surgery.
- May be found incidentally, e.g. during C-section.
Gross
Microscopic
Features:
- Benign mesothelium.
- Single layer of squamoid or cuboid mesothelial cells.[5]
IHC
- CK +ve, calretinin +ve.[5]
Pregnancy luteoma
General
- Tumour of pregnancy.
- Benign.
- Regress after pregnancy; thus, conservative management.[6]
Clinical:
- Increased serum testosterone.[7]
Microscopic
Features:
- Sheets of cells.
- Cells with eosinophilic cytoplasm, round nuclei and prominent nucleoli.
DDx:
See also
References
- ↑ IAV. 6 February 2009.
- ↑ Auersperg N, Wong AS, Choi KC, Kang SK, Leung PC (April 2001). "Ovarian surface epithelium: biology, endocrinology, and pathology". Endocr. Rev. 22 (2): 255–88. PMID 11294827. http://edrv.endojournals.org/cgi/pmidlookup?view=long&pmid=11294827.
- ↑ ALS. 5 February 2009.
- ↑ GAG 26 Feb 2009.
- ↑ 5.0 5.1 5.2 Urbanczyk K, Skotniczny K, Kucinski J, Friediger J (2005). "Mesothelial inclusion cysts (so-called benign cystic mesothelioma)--a clinicopathological analysis of six cases". Pol J Pathol 56 (2): 81-7. PMID 16092670.
- ↑ Masarie, K.; Katz, V.; Balderston, K. (Sep 2010). "Pregnancy luteomas: clinical presentations and management strategies.". Obstet Gynecol Surv 65 (9): 575-82. doi:10.1097/OGX.0b013e3181f8c41d. PMID 21144088.
- ↑ Kao, HW.; Wu, CJ.; Chung, KT.; Wang, SR.; Chen, CY.. "MR imaging of pregnancy luteoma: a case report and correlation with the clinical features.". Korean J Radiol 6 (1): 44-6. PMID 15782020.