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Difference between revisions of "Esophagus"
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→Barrett esophagus: tweak
(→Barrett's esophagus: chg name) |
(→Barrett esophagus: tweak) |
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==Barrett esophagus== | ==Barrett esophagus== | ||
===General=== | ===General=== | ||
*Diagnosis is | *Diagnosis is made by '''clinicans ''not'' pathologists'''. | ||
** | **A common histologic correlate is metaplastic transformation of stratified squamous epithelium to simple columnar epithelium with goblet cells. | ||
***There is disagreement whether goblet cells are required for the diagnosis.<ref name=pmid19623166>{{Cite journal | last1 = Riddell | first1 = RH. | last2 = Odze | first2 = RD. | title = Definition of Barrett's esophagus: time for a rethink--is intestinal metaplasia dead? | journal = Am J Gastroenterol | volume = 104 | issue = 10 | pages = 2588-94 | month = Oct | year = 2009 | doi = 10.1038/ajg.2009.390 | PMID = 19623166 }}</ref> | |||
*Associated with chronic reflux. | *Associated with chronic reflux - ''see: [[gastroesophageal reflux disease]]''. | ||
Significance of Barrett's esophagus: | |||
*Increased risk of adenocarcinoma of the esophagus. | *Increased risk of adenocarcinoma of the esophagus. | ||
**Need on-going surveillance, i.e. long term follow-up/repeat esophagogastroduodenoscopy. | **Need on-going surveillance, i.e. long term follow-up/repeat esophagogastroduodenoscopy. | ||