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Difference between revisions of "Lung tumours"
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→Typical carcinoid lung tumour: more
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(→Typical carcinoid lung tumour: more) |
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==Typical carcinoid lung tumour== | ==Typical carcinoid lung tumour== | ||
*[[AKA]] ''carcinoid of the lung''. | *[[AKA]] ''carcinoid tumour of the lung''. | ||
===General=== | ===General=== | ||
*Approximately 80% of lung carcinoids.<ref name=pmid20888248>{{Cite journal | last1 = Naalsund | first1 = A. | last2 = Rostad | first2 = H. | last3 = Strøm | first3 = EH. | last4 = Lund | first4 = MB. | last5 = Strand | first5 = TE. | title = Carcinoid lung tumors--incidence, treatment and outcomes: a population-based study. | journal = Eur J Cardiothorac Surg | volume = 39 | issue = 4 | pages = 565-9 | month = Apr | year = 2011 | doi = 10.1016/j.ejcts.2010.08.036 | PMID = 20888248 }}</ref> | *Approximately 80% of lung carcinoids.<ref name=pmid20888248>{{Cite journal | last1 = Naalsund | first1 = A. | last2 = Rostad | first2 = H. | last3 = Strøm | first3 = EH. | last4 = Lund | first4 = MB. | last5 = Strand | first5 = TE. | title = Carcinoid lung tumors--incidence, treatment and outcomes: a population-based study. | journal = Eur J Cardiothorac Surg | volume = 39 | issue = 4 | pages = 565-9 | month = Apr | year = 2011 | doi = 10.1016/j.ejcts.2010.08.036 | PMID = 20888248 }}</ref> | ||
| Line 164: | Line 164: | ||
*No necrosis. | *No necrosis. | ||
*Low mitotic rate. | *Low mitotic rate. | ||
DDx: | |||
*[[Atypical carcinoid lung tumour]]. | |||
===IHC=== | |||
*MIB-1 scant staining. | |||
==Atypical carcinoid lung tumour== | |||
*[[AKA]] ''carcinoid tumour of the lung''. | |||
===General=== | |||
*Approximately 20% of lung carcinoids.<ref name=pmid20888248>{{Cite journal | last1 = Naalsund | first1 = A. | last2 = Rostad | first2 = H. | last3 = Strøm | first3 = EH. | last4 = Lund | first4 = MB. | last5 = Strand | first5 = TE. | title = Carcinoid lung tumors--incidence, treatment and outcomes: a population-based study. | journal = Eur J Cardiothorac Surg | volume = 39 | issue = 4 | pages = 565-9 | month = Apr | year = 2011 | doi = 10.1016/j.ejcts.2010.08.036 | PMID = 20888248 }}</ref> | |||
===Microscopic=== | |||
Features: | |||
*Nests of cells. | |||
**Stippled chromatin. | |||
**Mild-to-moderate amount of cytoplasm. | |||
*No necrosis. | |||
*Moderate mitotic rate. | |||
DDx: | |||
*[[Typical carcinoid lung tumour]]. | |||
*[[Small cell carcinoma of the lung]]. | |||
===IHC=== | ===IHC=== | ||
MIB-1 | *MIB-1 moderate staining. | ||
==Malignant mesothelioma== | ==Malignant mesothelioma== | ||