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Difference between revisions of "Vasculitides"
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→Medium vessel vasculitides: +kawasaki disease
(→Overview: w) |
(→Medium vessel vasculitides: +kawasaki disease) |
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=Medium vessel vasculitides= | =Medium vessel vasculitides= | ||
The follow section has information specific to the individual types of medium vessel vasculitis. | The follow section has information specific to the individual types of medium vessel vasculitis. | ||
==Kawasaki disease== | |||
===General=== | |||
*Medium vessel disease. | |||
*Classically afflicts the coronary arteries of children. | |||
Clinical features '''Warm CREAM'':<ref>URL: [http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?&system=Other%2FMiscellaneous&discipline=Pathology&browse=1 http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?&system=Other%2FMiscellaneous&discipline=Pathology&browse=1]. Accessed on: 14 January 2012.</ref> | |||
*Fever. | |||
*Conjunctivitis, non-exudative. | |||
*Rash, polymorphous. | |||
*Erythema or edema of hands and feet. | |||
*Adenopathy, usu. cervical and unilateral. | |||
*Mucosal manifestations - strawberry tongue, cracked lips. | |||
Treatment: | |||
*High dose IV aspirin. | |||
===Microscopic=== | |||
Features: | |||
*Medium-sized vessels with intramural inflammatory cells. | |||
*Vessel destruction, e.g. [[fibrinoid necrosis]] (very pink anucleate arterial wall). | |||
==Polyarteritis nodosa== | ==Polyarteritis nodosa== | ||