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Difference between revisions of "Endometrium"
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*Too much bleeding (if premenopausal) - ''AUB'' = abnormal uterine bleeding. | *Too much bleeding (if premenopausal) - ''AUB'' = abnormal uterine bleeding. | ||
*Post-menopausal bleeding. | *Post-menopausal bleeding. | ||
*Dysfunctional uterine bleeding aka ''DUB'' | *Dysfunctional uterine bleeding aka ''DUB'' - may get D&C if they fail medical management.<ref>URL: [http://emedicine.medscape.com/article/257007-treatment http://emedicine.medscape.com/article/257007-treatment]. Accessed on: 15 July 2010.</ref> | ||
**DUB is diagnosed if other causes of bleeding are excluded - these patients are | **DUB is diagnosed if other causes of bleeding are excluded - these patients are usually managed medically. | ||
Micro. | Micro. | ||
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===Microscopy=== | ===Microscopy=== | ||
Features:<ref>[http://www.pathologyoutlines.com/uterus.html#endopolyp http://www.pathologyoutlines.com/uterus.html#endopolyp]</ref> | Features:<ref>URL: [http://www.pathologyoutlines.com/uterus.html#endopolyp http://www.pathologyoutlines.com/uterus.html#endopolyp].</ref> | ||
*Large blood vessels (muscular) - '''key feature'''. | *Large blood vessels (muscular) - '''key feature'''. | ||
*Fibrotic stroma - '''key feature'''. | *Fibrotic stroma - '''key feature'''. | ||
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*Mid secretory phase - post-ovulatory day 6-8: | *Mid secretory phase - post-ovulatory day 6-8: | ||
** | **Glands: Mucus in glands. | ||
** | **Stroma: Edema (empty space around the glands). | ||
*Late secretory phase (begining) - post-ovulatory day 9-12: | *Late secretory phase (begining) - post-ovulatory day 9-12: | ||
** | **Stroma: | ||
** | ***Spiral arterioles. | ||
***Nucleus central. | ***Predecidual changes -- mnemonic ''NEW'': | ||
***Eosinophilic cytoplasm '''key feature''' (may be subtle to the novice). | ***#Nucleus central. | ||
***Well-defined cell borders. | ***#Eosinophilic cytoplasm '''key feature''' (may be subtle to the novice). | ||
***#Well-defined cell borders. | |||
*Premenstrual | *Premenstrual | ||
** | **Stroma: Neutrophils, scattered lymphocytes, stromal balls ("blue balls"); "stromal condensation" (Image: [http://commons.wikimedia.org/wiki/File:Endometrial_stromal_condensation_high_mag.jpg Endometrial stromal condensation (WC)]). | ||
** | **Glands: Apoptosis at the base of the gland.<ref>TC. 22 June 2009.</ref> | ||
General refs.: <ref>{{Ref PBoD|1081}}</ref><ref>{{Ref DCHH|237}}</ref> | General refs.: <ref>{{Ref PBoD|1081}}</ref><ref>{{Ref DCHH|237}}</ref> | ||
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==Endometrial hyperplasia== | ==Endometrial hyperplasia== | ||
{{main|Endometrial hyperplasia}} | {{main|Endometrial hyperplasia}} | ||
Can be thought of as a precursor lesion for endometrial carcinoma. | |||
==Endometrial carcinoma== | ==Endometrial carcinoma== | ||
{{main|Endometrial carcinoma}} | {{main|Endometrial carcinoma}} | ||
A very common gynecologic malignancy. | |||
==See also== | ==See also== | ||
*[[Uterine tumours]]. | *[[Uterine tumours]]. | ||
*[[Gynecologic pathology]]. | |||
==References== | ==References== | ||