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Difference between revisions of "Gastrointestinal tract polyps"
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Gastrointestinal tract polyps (view source)
Revision as of 12:56, 13 July 2010
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===Peutz-Jeghers polyp=== | ===Peutz-Jeghers polyp=== | ||
==== | ====Epidemiology==== | ||
Features:<ref name=Ref_PBoD859/><ref name=pmid12692201>{{Cite journal | last1 = Bronner | first1 = MP. | title = Gastrointestinal inherited polyposis syndromes. | journal = Mod Pathol | volume = 16 | issue = 4 | pages = 359-65 | month = Apr | year = 2003 | doi = 10.1097/01.MP.0000062992.54036.E4 | PMID = 12692201 | url = http://www.nature.com/modpathol/journal/v16/n4/full/3880773a.html }}</ref> | Features:<ref name=Ref_PBoD859/><ref name=pmid12692201>{{Cite journal | last1 = Bronner | first1 = MP. | title = Gastrointestinal inherited polyposis syndromes. | journal = Mod Pathol | volume = 16 | issue = 4 | pages = 359-65 | month = Apr | year = 2003 | doi = 10.1097/01.MP.0000062992.54036.E4 | PMID = 12692201 | url = http://www.nature.com/modpathol/journal/v16/n4/full/3880773a.html }}</ref> | ||
*Peutz-Jeghers syndrome is autosomal dominant. | *Peutz-Jeghers syndrome is autosomal dominant. | ||
*Altered gene: STK11. | *Altered gene: STK11. | ||
====Clinical==== | |||
Features:<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/175200 http://www.ncbi.nlm.nih.gov/omim/175200]. Accessed on: 13 July 2010.</ref> | |||
*Melanocytic macules. | |||
**Lips, buccal mucosa, and digits. | |||
**Multiple Peutz-Jeghers polyps | |||
Increased risk of various neoplasms - primarily: | |||
*Breast and gastrointestinal cancer.<ref name=pmid20581245>{{cite journal |author=Beggs AD, Latchford AR, Vasen HF, ''et al.'' |title=Peutz-Jeghers syndrome: a systematic review and recommendations for management |journal=Gut |volume=59 |issue=7 |pages=975–86 |year=2010 |month=July |pmid=20581245 |doi=10.1136/gut.2009.198499 |url=}}</ref> | |||
====Microscopy==== | ====Microscopy==== | ||