Difference between revisions of "Placenta"

Placenta (view source)

686 bytes added , 03:18, 13 July 2010

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 ===Hypertrophic decidual vasculopathy===
-Features:<ref>AFIP - Placental Pathology. P.122. ISBN: 1-881041-89-1. 2004.</ref>
+Features:<ref name=pmid18641412>{{Cite journal  | last1 = Roberts | first1 = DJ. | last2 = Post | first2 = MD. | title = The placenta in pre-eclampsia and intrauterine growth restriction. | journal = J Clin Pathol | volume = 61 | issue = 12 | pages = 1254-60 | month = Dec | year = 2008 | doi = 10.1136/jcp.2008.055236 | PMID = 18641412 }}</ref>
-*Narrowing of decidual spiral arteries.
+*Mild or moderate:
-**Due to excessive (vascular smooth) muscle. (???)
+*#Perivascular inflammatory cells.
+*#+/-Vascular thrombosis.
+*#Smooth muscle hypertrophy.
+*#Endothelial hyperplasia.
+*#*Above two lead to narrowing of the decidual spiral arteries<ref>AFIP - Placental Pathology. P.122. ISBN: 1-881041-89-1. 2004.</ref> -- '''key feature'''.
+*Severe:<ref name=pmid18641412/>
+*#Atherosis - foamy macrophages within vascular wall.
+*#Fibrinoid necrosis of vessel wall (amorphous eosinophilic vessel wall).
+General:
+*Seen in intrauterine growth restriction (IUGR).
 ===Atherosis===