Difference between revisions of "Nucleus-to-cytoplasm ratio"
Jump to navigation
Jump to search
(create) |
(No difference)
|
Revision as of 23:11, 27 December 2011
Nucleus-to-cytoplasm ratio, also nuclear-cytoplasmic ratio, is the relative size of the nucleus to the cytoplasm. It is commonly abbreviated NC ratio.
High NC ratio is strong predictor of malignancy.[1] Like very rule, there are exceptions:
High NC ratio in normal cells:
- Lymphocytes.
Low NC ratio in cancer:
The classic malignant high NC ratio cell is:
Other malignant high NC ratio tumours are the small round cell tumours.
See also
References
- ↑ Mehrotra, R.; Gupta, A.; Singh, M.; Ibrahim, R. (2006). "Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions.". Mol Cancer 5: 11. doi:10.1186/1476-4598-5-11. PMID 16556320.