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==General== | ==General== | ||
*Benign. | |||
===Uterine leiomyomas=== | |||
*Often called "fibroids". | *Often called "fibroids". | ||
*Extremely common... 40% of women by age 40. | *Extremely common... 40% of women by age 40. | ||
*Can be a cause of [[AUB]] (abnormal uterine bleeding). | |||
*Large & multiple leiomyomas are associated with infertility. | |||
==Gross== | ==Gross== | ||
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* Whorled appearance. | * Whorled appearance. | ||
Factors that raise concern for [[leiomyosarcoma]]: | |||
* Haemorrhage. | * Haemorrhage. | ||
* Cystic degeneration. | * Cystic degeneration. | ||
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==IHC== | ==IHC== | ||
Work-up of suspicious leiomyomas:<ref>STC. 25 February 2009.</ref> | Work-up of suspicious leiomyomas:<ref>STC. 25 February 2009.</ref> | ||
*CD10 | *CD10 +ve. | ||
*Ki-67 | *Ki-67 -ve. | ||
*SMA | *SMA +ve. | ||
*Desmin | *Desmin +ve. | ||
==See also== | ==See also== | ||
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==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Soft tissue lesions]] | [[Category:Soft tissue lesions]] |
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