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Difference between revisions of "Clear cell renal cell carcinoma"
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Clear cell renal cell carcinoma (view source)
Revision as of 21:11, 8 January 2016
, 21:11, 8 January 2016no edit summary
| Line 13: | Line 13: | ||
| Molecular = | | Molecular = | ||
| IF = | | IF = | ||
| Gross = golden/yellow colour, +/-hemorrhagic, +/-cystic, +/-necrosis | | Gross = golden/yellow colour, +/-hemorrhagic, +/-cystic, +/-[[necrosis]] | ||
| Grossing = [[total nephrectomy for tumour grossing]], [[partial nephrectomy grossing]] | | Grossing = [[total nephrectomy for tumour grossing]], [[partial nephrectomy grossing]] | ||
| Staging = [[kidney cancer staging]] | | Staging = [[kidney cancer staging]] | ||
| Line 84: | Line 84: | ||
**Not common in papillary RCC. | **Not common in papillary RCC. | ||
*Clear cytoplasm - due to lipid content. | *Clear cytoplasm - due to lipid content. | ||
*[[Necrosis]] is | *[[Necrosis]] is independent predictor of outcome - if present in a significant quantity:<ref name=pmid25474516>{{Cite journal | last1 = Renshaw | first1 = AA. | last2 = Cheville | first2 = JC. | title = Quantitative tumour necrosis is an independent predictor of overall survival in clear cell renal cell carcinoma. | journal = Pathology | volume = 47 | issue = 1 | pages = 34-7 | month = Jan | year = 2015 | doi = 10.1097/PAT.0000000000000193 | PMID = 25474516 }}</ref> | ||
**>30% is significant for pT3a tumours. | **>30% is significant for pT3a tumours. | ||
**>20% is significant for pT1-2 pN0 tumours. | **>20% is significant for pT1-2 pN0 tumours. | ||