View source for Prophylactic bilateral salpingo-oophorectomy

'''Prophylactic bilateral salpingo-oophorectomy''' are done to prevent the development of cancer - when there is a genetic predisposition.

==General==
*The pathology yield in ''prophylactic bilateral salpingo-oophorectomies'' is significant but modest; in series of 26 prophylatic surgeries (BRCA1 22 individuals, BRCA2 4 individuals) there were 2 in situ carcinoma and 2 atypical proliferations.<ref name=pmid14668548>{{Cite journal  | last1 = Carcangiu | first1 = ML. | last2 = Radice | first2 = P. | last3 = Manoukian | first3 = S. | last4 = Spatti | first4 = G. | last5 = Gobbo | first5 = M. | last6 = Pensotti | first6 = V. | last7 = Crucianelli | first7 = R. | last8 = Pasini | first8 = B. | title = Atypical epithelial proliferation in fallopian tubes in prophylactic salpingo-oophorectomy specimens from BRCA1 and BRCA2 germline mutation carriers. | journal = Int J Gynecol Pathol | volume = 23 | issue = 1 | pages = 35-40 | month = Jan | year = 2004 | doi = 10.1097/01.pgp.0000101082.35393.84 | PMID = 14668548 }}</ref> All of the pathology was in BRCA1 carriers.

==Grossing==
*Submit ovaries and tubes in total.<ref>{{cite journal |authors=Fedda FA, Euscher ED, Ramalingam P, Malpica A |title=Prophylactic Risk-reducing Hysterectomies and Bilateral Salpingo-oophorectomies in Patients With Lynch Syndrome: A Clinicopathologic Study of 29 Cases and Review of the Literature |journal=Int J Gynecol Pathol |volume=39 |issue=4 |pages=313–320 |date=July 2020 |pmid=31851061 |doi=10.1097/PGP.0000000000000643 |url=}}</ref><ref>{{cite journal |authors=Mingels MJ, Roelofsen T, van der Laak JA, de Hullu JA, van Ham MA, Massuger LF, Bulten J, Bol M |title=Tubal epithelial lesions in salpingo-oophorectomy specimens of BRCA-mutation carriers and controls |journal=Gynecol Oncol |volume=127 |issue=1 |pages=88–93 |date=October 2012 |pmid=22710074 |doi=10.1016/j.ygyno.2012.06.015 |url=}}</ref>

==Sign out==
<pre>
Fallopian Tubes and Ovaries, Bilateral Salpingo-Oophorectomy:
	- Benign ovaries and Fallopian tubes.
	- NEGATIVE for malignancy.
</pre>

==See also==
*[[Ovarian tumours]].
*[[Hereditary breast cancer]].
*[[Sectioning and extensively examining of the fimbriated end]] (SEE-FIM).

==References==
{{Reflist|1}}

[[Category:Gynecologic pathology]]