View source for Case 7

===Clinical history===
67 year old man, cervical lymphadenopathy.

===Primary image===
[[Image:Rosai-Dorfman disease - very high mag.jpg|500px|link=|center|]]
<center>Very high magnification. [[H&E stain]].</center>

{{hidden|Very high magnification|[[Image:Emperipolesis - very high mag.jpg|500px|link=|center|]]
<center>Very high magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>[[histiocytoses]] - [[sinus histiocytosis]], [[Rosai-Dorfman disease]]</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>No constitutional symptoms. Anemia NYD.</center>}}

====Ask a friend====
{{hidden|Ask a friend|<center>Looks like rare bird. Did you order a S-100?</center>}}

====Stains====
{{Case Stains
| blank=Dr T would ask why!
| alcpas= 
| alc1= 
| alc25= 
| aur= 
| biel= 
| bili= 
| iron= 
| congored= 
| cresylv= 
| diffquik= 
| fontana= 
| gallyas= 
| giemsa= 
| gms= 
| gomori= 
| gram= 
| gremelius= 
| jms= 
| jones= 
| kinyoun= 
| luxol= 
| masson= 
| mmas= 
| mucicar= 
| oilredo= 
| orecein= 
| pas= 
| pasd= 
| pasf= 
| ptah= 
| prussian= 
| reticulin= 
| sudanblackb= 
| toluidine= 
| verhoeff= 
| vonkossa= 
| warthinstarry= 
}}

====IHC====
{{Case IHC
| blank=Dr T would ask why!
| ae1ae3= 
| a1at= 
| acth= 
| afp= 
| alk1= 
| amacr=
| b2microgl= 
| b723= 
| bcl2= 
| bcl6= 
| bclxl= 
| c3= 
| calcit= 
| calponin= 
| calretinin= 
| cd10= 
| cd117= 
| cd15= 
| cd1a= '''NEGATIVE''' 
| cd20= 
| cd21= 
| cd23= 
| cd3= 
| cd30= 
| cd31= 
| cd34= 
| cd35= 
| cd4= 
| cd43= 
| cd45= 
| cd5= 
| cd56= 
| cd68= '''POSITIVE'''
| cd7= 
| cd79a= 
| cd8= 
| cd99= 
| cea= 
| chromo= 
| ck19= 
| ck20= 
| ck34be12= 
| ck7= 
| cmv= 
| cmyc= 
| cyclind1= 
| desmin= 
| ebv= 
| ema= 
| erpr= 
| fascin= 
| fsh= 
| fviii= 
| fxiiia= 
| gastrin= 
| gcdfp= 
| gh= 
| glucag= 
| hbme1= 
| hbvc= 
| hbvs= 
| hcg= 
| hepatocyte= 
| her2= 
| hmb45= 
| hpv= 
| hsv1= 
| hsv2= 
| inhibin= 
| insulin= 
| kappa= 
| ki67= 
| lambda= 
| lca= 
| leu7= 
| lga= 
| lgg= 
| lgm= 
| lh= 
| lysozyme= 
| melanina= 
| myleoperox= 
| myod1= 
| myog= 
| myog= 
| nse= 
| p53= 
| p63= 
| panker= 
| pcna= 
| plap= 
| pnl2c= 
| prolac= 
| psa= 
| s100= '''POSITIVE'''
| sma=  
| somatsat= 
| synapto= 
| tdt= 
| thyrogl= 
| toxopl= 
| tsh= 
| ttf1= '''NEGATIVE'''
| ubiquitin= 
| uchl1= 
| ulexeurope= 
| vim= 
| vip= 
| vzv= 
}}

===Diagnosis===
{{hidden|Diagnosis|<center>[[Rosai-Dorfman disease]]</center>}}

__NOTOC__

[[Category:Cases]]
[[Category:Cases in lymph node pathology]]
[[Category:Cases difficulty 5]]