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Difference between revisions of "Langerhans cell histiocytosis"
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Langerhans cell histiocytosis (view source)
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'''Langerhans cell histiocytosis''', abbreviated '''LCH''', is a rare genetic disorder of tissue macrophages. It broadly fits into the category of ''[[histiocytoses]]''. | '''Langerhans cell histiocytosis''', abbreviated '''LCH''', is a rare genetic disorder of tissue macrophages. It broadly fits into the category of ''[[histiocytoses]]''. | ||
==General== | |||
*Looks like eosinophilic granuloma of the lung - see ''[[Medical_lung_diseases#Pulmonary_Langerhans_cell_histiocytosis|medical lung diseases]]''. | *Looks like eosinophilic granuloma of the lung - see ''[[Medical_lung_diseases#Pulmonary_Langerhans_cell_histiocytosis|medical lung diseases]]''. | ||
==Microscopic== | |||
Features: | Features: | ||
*Langerhans cells histiocytes - '''key feature'''. | *Langerhans cells histiocytes - '''key feature'''. | ||
| Line 20: | Line 20: | ||
*See ''[[lymph node pathology]]''. | *See ''[[lymph node pathology]]''. | ||
==IHC== | |||
*CD1a +ve. | *CD1a +ve. | ||
*S100 +ve. | *S100 +ve. | ||
==Electron microscopy== | |||
*[[Birbeck granules]]. | *[[Birbeck granules]]. | ||