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Difference between revisions of "An introduction to head and neck pathology"
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An introduction to head and neck pathology (view source)
Revision as of 17:47, 1 September 2011
, 17:47, 1 September 2011→Pyogenic granuloma: more, +IHC
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*Sometimes ''pregnancy tumour''. | *Sometimes ''pregnancy tumour''. | ||
*Seen in children, young adults, pregnant women. | *Seen in children, young adults, pregnant women. | ||
Clinical: | |||
*May grow quickly - clinically suspicious for a malignancy. | |||
Notes: | |||
*Name of entity is a misnomer: | |||
**Not pyogenic, i.e. infectious. | |||
**Not [[granuloma|granulomatous]]. | |||
*The WMSP advocates the name ''lobular capillary hemangioma''.<ref name=Ref_WMSP12>{{Ref WMSP|12}}</ref> | |||
===Gross=== | ===Gross=== | ||
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*Erythematous. | *Erythematous. | ||
*Hemorrhagic. | *Hemorrhagic. | ||
Usually location:<ref name=Ref_WMSP12>{{Ref WMSP|12}}</ref> | |||
*Lips. | |||
*Tongue. | |||
*Gingiva. | |||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_PBoD775>{{Ref PBoD|775}}</ref> | Features:<ref name=Ref_PBoD775>{{Ref PBoD|775}}</ref> | ||
*Vascular, i.e. many blood vessels | *Polypoid ''or'' peduculated. | ||
*Vascular, i.e. many blood vessels, with plump endothelium. | |||
*Usu. thinned epithelium | *Usu. thinned epithelium<ref>URL: [http://basicpathology-histopathology.blogspot.com/2009/10/head-and-neck-oral-cavity-reactive_3282.html http://basicpathology-histopathology.blogspot.com/2009/10/head-and-neck-oral-cavity-reactive_3282.html]. Accessed on: 2 February 2011.</ref> or ulcerated.<ref name=Ref_WMSP12>{{Ref WMSP|12}}</ref> | ||
DDx: | DDx: | ||
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*[http://www.sciencephoto.com/images/download_lo_res.html?id=670066054 Pyogenic granuloma (sciencephoto.com)]. | *[http://www.sciencephoto.com/images/download_lo_res.html?id=670066054 Pyogenic granuloma (sciencephoto.com)]. | ||
===IHC=== | |||
* | Features - positive for vascular markers:<ref name=Ref_WMSP12>{{Ref WMSP|12}}</ref> | ||
* | *CD34 +ve. | ||
* | *CD31 +ve. | ||
*Factor VIIIa +ve. | |||
==Hairy leukoplakia== | ==Hairy leukoplakia== | ||