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'''Nuclear pseudoinclusions''' are | [[Image:Thyroid papillary carcinoma histopathology (4).jpg|thumb|right|A pseudoinclusion in [[papillary thyroid carcinoma]].]] | ||
'''Nuclear pseudoinclusions''' are cytoplasmic invaginations into the nucleus that mimic true nuclear inclusion. | |||
Tumours | ==Nuclear pseudoinclusions and true nuclear inclusions== | ||
*Papillary thyroid carcinoma. | True nuclear inclusions consist of material that is: | ||
*Melanoma. | # Foreign to the nucleus. | ||
*Adenocarcinoma of the lung. | # Completely contained within the nucleus. | ||
*Meningioma.<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/neurotest/Q51-Ans.htm http://moon.ouhsc.edu/kfung/jty1/neurotest/Q51-Ans.htm]. Accessed on: 25 October 2010.</ref> | |||
They are classically caused by viral particles; however, there are other causes.<ref name=pmid21081532>{{Cite journal | last1 = Ip | first1 = YT. | last2 = Dias Filho | first2 = MA. | last3 = Chan | first3 = JK. | title = Nuclear inclusions and pseudoinclusions: friends or foes of the surgical pathologist? | journal = Int J Surg Pathol | volume = 18 | issue = 6 | pages = 465-81 | month = Dec | year = 2010 | doi = 10.1177/1066896910385342 | PMID = 21081532 }}</ref> | |||
==Tumours with pseudoinclusions== | |||
*[[Papillary thyroid carcinoma]]. | |||
*[[Medullary thyroid carcinoma]].<ref>URL: [http://www.papsociety.org/guidelines/Morphologic%20criteria.doc http://www.papsociety.org/guidelines/Morphologic%20criteria.doc]. Accessed on: 28 April 2010.</ref> | |||
*[[Melanoma]]. | |||
*[[Adenocarcinoma of the lung]]. | |||
*[[Meningioma]].<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/neurotest/Q51-Ans.htm http://moon.ouhsc.edu/kfung/jty1/neurotest/Q51-Ans.htm]. Accessed on: 25 October 2010.</ref><ref name=Ref_PSNP194>{{Ref PSNP|194}}</ref> | |||
Note: | |||
*The above is not an exhaustive list. | |||
==Pseudoinclusions in benign processes== | |||
*[[Arias-Stella reaction]].<ref name=pmid11756756>{{Cite journal | last1 = Arias-Stella | first1 = J. | title = The Arias-Stella reaction: facts and fancies four decades after. | journal = Adv Anat Pathol | volume = 9 | issue = 1 | pages = 12-23 | month = Jan | year = 2002 | doi = | PMID = 11756756 }}</ref> | |||
**May mimic [[HSV]].<ref name=pmid6284466>{{Cite journal | last1 = Dardi | first1 = LE. | last2 = Ariano | first2 = L. | last3 = Ariano | first3 = MC. | last4 = Gould | first4 = VE. | title = Arias-Stella reaction with prominent nuclear pseudoinclusions simulating herpetic endometritis. | journal = Diagn Gynecol Obstet | volume = 4 | issue = 2 | pages = 127-32 | month = | year = 1982 | doi = | PMID = 6284466 }}</ref> | |||
==See also== | ==See also== | ||
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==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Basics]] | [[Category:Basics]] |
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