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'''Two vessel umbilical cord''', also '''two vessel cord''' and '''single umbilical artery''', is an abnormality seen in [[placenta|placental pathology]]. | |||
==General== | |||
Associations: | |||
*Associated with congenital abnormalities, esp. cardiac - '''key point'''.<ref name=Ref_WMSP464>{{Ref WMSP|464}}</ref> | |||
**Thought to be an acquired defect (as prevalence is lower early in gestation). | |||
*May be seen in association of other cord abnormalities (e.g. marginal insertion, velamentous insertion). | |||
*In apparently well (liveborn) infants it is associated with (occult) renal abnormalities, specifically vesico-ureteric reflux; there is no evidence for other abnormalities.<ref name=pmid15613529>{{cite journal |author=Srinivasan R, Arora RS |title=Do well infants born with an isolated single umbilical artery need investigation? |journal=Arch. Dis. Child. |volume=90 |issue=1 |pages=100–1 |year=2005 |month=January |pmid=15613529 |pmc=1720078 |doi=10.1136/adc.2004.062372 |url=}}</ref> | |||
*Associated with maternal [[diabetes]].<ref name=pmid7997408>{{cite journal |author=Lilja M |title=Infants with single umbilical artery studied in a national registry. 3: A case control study of risk factors |journal=Paediatr Perinat Epidemiol |volume=8 |issue=3 |pages=325–33 |year=1994 |month=July |pmid=7997408 |doi= |url=}}</ref> | |||
==Gross== | |||
*Two vessels in the umbilical cord. | |||
==Microscopic== | |||
Features: | |||
*Two vessels in the umbilical cord - one artery and one vein. | |||
===Image=== | |||
<gallery> | |||
Image:Single_umbilical_artery,_HE..jpg | Single umbilical artery. (WC/Patho) | |||
</gallery> | |||
www: | |||
*[http://www.glowm.com/resources/glowm/graphics/figures/v2/1070/05b.jpg SUA (glown.com)].<ref>URL: [http://www.glowm.com/?p=glowm.cml/section_view&articleid=151 http://www.glowm.com/?p=glowm.cml/section_view&articleid=151]. Accessed on: 8 January 2011.</ref> | |||
==Sign out== | |||
<pre> | |||
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CAESAREAN SECTION: | |||
- TWO VESSEL UMBILICAL CORD, NEGATIVE FOR INFLAMMATION. | |||
- FETAL MEMBRANES WITHIN NORMAL LIMITS. | |||
- PLACENTAL DISC WITH THIRD TRIMESTER VILLI WITHOUT APPARENT PATHOLOGY. | |||
</pre> | |||
===With meconium=== | |||
<pre> | |||
PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CAESAREAN SECTION: | |||
- TWO VESSEL UMBILICAL CORD, NEGATIVE FOR INFLAMMATION. | |||
- FETAL MEMBRANES WITH FOCAL PIGMENTED CELLS CONSISTENT WITH MECONIUM, | |||
NEGATIVE FOR APPARENT CHORIOAMNIONITIS. | |||
- PLACENTAL DISC WITH THIRD TRIMESTER VILLI WITHOUT APPARENT PATHOLOGY. | |||
</pre> | |||
==See also== | |||
*[[Placenta]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Placenta]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] |
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