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''' | An '''oncogene''' is a [[cancer]] gene, derived from a '''proto-oncogene'''. | ||
Examples | ==Examples== | ||
{| class="wikitable sortable" | |||
! Gene | |||
! Cancer | |||
|- | |||
| EGFR<ref name=omim131550>{{OMIM|131550}}</ref> | |||
| [[lung adenocarcinoma]], [[glioblastoma]],<ref name=Ref_APBR419>{{Ref APBR|419 Q6}}</ref> [[anaplastic astrocytoma]]<ref name=Ref_APBR419>{{Ref APBR|419 Q6}}</ref> | |||
|- | |||
| PDGFB<ref name=omim190040>{{OMIM|190040}}</ref> | |||
| [[dermatofibrosarcoma protuberans]] | |||
|- | |||
| BRAF<ref name=omim164757>{{OMIM|164757}}</ref> | |||
| [[papillary thyroid carcinoma tall cell variant]] | |||
|- | |||
| [[KRAS mutation|KRAS]]<ref name=omim190070>{{OMIM|190070}}</ref> | |||
| [[invasive ductal carcinoma of the pancreas]] | |||
|- | |||
| MYC<ref name=omim190080>{{OMIM|190080}}</ref> | |||
| [[Burkitt lymphoma]] | |||
|- | |||
| MET<ref name=omim164860>{{OMIM|164860}}</ref> | |||
| [[papillary renal cell carcinoma]] | |||
|- | |||
| ERBB2 (HER2)<ref name=omim164870>{{OMIM|164870}}</ref> | |||
| [[invasive breast carcinoma]] | |||
|- | |||
| CCND1 (BCL1)<ref name=omim168461>{{OMIM|168461}}</ref> | |||
| [[mantle cell lymphoma]] | |||
|- | |||
| EWSR1<ref name=omim133450>{{OMIM|133450}}</ref> | |||
| [[Ewing sarcoma]], [[clear cell sarcoma]], [[DSRCT]], [[extraskeletal myxoid chondrosarcoma|EMC]] | |||
|} | |||
==See also== | ==See also== | ||
*[[Tumour suppressor gene]]. | *[[Tumour suppressor gene]]. | ||
*[[Molecular pathology]]. | *[[Molecular pathology]]. | ||
==References== | |||
{{Reflist|2}} | |||
[[Category:Molecular pathology]] | [[Category:Molecular pathology]] |
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