File:Urothelial dysplasia -- very high mag.jpg

From Libre Pathology
Jump to navigation Jump to search

Original file ‎(2,848 × 4,272 pixels, file size: 4.52 MB, MIME type: image/jpeg)

This file is from Wikimedia Commons and may be used by other projects. The description on its file description page there is shown below.

Summary

Description

Micrograph showing urothelial dysplasia. H&E stain/CK20 immunostain.

This case has significant mitotic activity without appreciable inflammation, nuclear hyperchromasia, and minimal maturation to the surface. The small nuclear size is more in keeping with dysplasia.

By definition, carcinoma in situ (CIS) has no maturation to the surface. Also, CIS typically has nuclear enlargement (nuclei 4-5x the size of a benign resting lymphocyte). The full thickness CK20 staining confirms dysplasia; however, it is not useful for differentiating urothelial dysplasia from CIS.

Related images

  • UD - low mag.
    UD - low mag.
  • UD - intermed. mag.
    UD - intermed. mag.
  • UD - high mag.
    UD - high mag.
  • UD - high mag.
    UD - high mag.
  • UD - very high mag.
    UD - very high mag.
  • UD - intermed. mag.
    UD - intermed. mag.
  • UD - high mag.
    UD - high mag.
  • UD - high mag.
    UD - high mag.
  • UD - very high mag.
    UD - very high mag.
  • UD - intermed. mag.
    UD - intermed. mag.
  • UD - high mag.
    UD - high mag.
Source Own work
Author Nephron

Licensing

I, the copyright holder of this work, hereby publish it under the following licenses:
w:en:Creative Commons
attribution share alike
This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
GNU head Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the section entitled GNU Free Documentation License.
You may select the license of your choice.

Captions

Add a one-line explanation of what this file represents

Items portrayed in this file

depicts

MIME type

image/jpeg

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current03:22, 9 August 2015Thumbnail for version as of 03:22, 9 August 20152,848 × 4,272 (4.52 MB)Nephron{{Information |Description =Micrograph showing '''urothelial dysplasia'''. H&E stain/CK20 immunostain. This case has significant mitotic activity without appreciable inflammation, nuclear hyperchromasia,...

The following page uses this file:

Retrieved from "https://librepathology.org/wiki/File:Urothelial_dysplasia_--_very_high_mag.jpg"