File:Bowenoid actinic keratosis - very high mag.jpg

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Description
English: Very high magnification micrograph of a bowenoid actinic keratosis, abbreviated BAK. H&E stain.

BAK involves the full thickness of the epidermis. It is differentiated from Bowen's disease (squamous cell carcinoma in situ) by the lack of involvement of the adnexal epithelium and folliclar epithelium.[1] Actinic keratosis (not otherwise specified) has a non-neoplastic superficial epidermis.

The section shows atypical basilar and suprabasilar cells with parakeratosis. Scattered atypical cells are present more superficial.

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References

  1. (Feb 2010). "Expression of p53 and p16 in actinic keratosis, bowenoid actinic keratosis and Bowen's disease.". J Eur Acad Dermatol Venereol 24 (2): 228-30. DOI:10.1111/j.1468-3083.2009.03337.x.
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Author Nephron

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current18:44, 21 May 2012Thumbnail for version as of 18:44, 21 May 20122,848 × 4,272 (4.13 MB)Nephron background (white), small fix

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