Tumour suppressor gene

From Libre Pathology
Revision as of 06:13, 16 December 2014 by Michael (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

A tumour suppressor gene is a gene that acts to protect the organism which it is within from developing cancer.


Gene Syndrome or disease
TP53 (p53)[1] Li-Fraumeni syndrome
BRCA1[2] Familial breast-ovarian cancer 1
RB1[3] Retinoblastoma
VHL[4] Von Hippel-Lindau disease
NF1[5] Neurofibromatosis type 1
TSC1[6] (hamartin) Tuberous sclerosis
TSC2[6] (tuberin) Tuberous sclerosis

See also


  1. Online 'Mendelian Inheritance in Man' (OMIM) 191170
  2. Online 'Mendelian Inheritance in Man' (OMIM) 113705
  3. Online 'Mendelian Inheritance in Man' (OMIM) 614041
  4. Online 'Mendelian Inheritance in Man' (OMIM) 608537
  5. Online 'Mendelian Inheritance in Man' (OMIM) 613113
  6. 6.0 6.1 Johnson, MW.; Kerfoot, C.; Bushnell, T.; Li, M.; Vinters, HV. (Mar 2001). "Hamartin and tuberin expression in human tissues.". Mod Pathol 14 (3): 202-10. doi:10.1038/modpathol.3880286. PMID 11266527.