Testicular metastasis

From Libre Pathology
Jump to navigation Jump to search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
Testicular metastasis
Diagnosis in short

Testis with metastatic prostate carcinoma. H&E stain. (WC)

Synonyms testicle with metastatic disease

LM atypical cells between seminiferous tubules, negative for GCNIS, +/-lymphovascular invasion
IHC IHC dependent on primary site (usually OCT4 -ve, AFP -ve, beta-hCG -ve, SALL4 -ve)
Site testis

Clinical history +/-history of malignancy
Signs testicular mass
Prevalence rare - esp. as first presentation
Prognosis poor
Clin. DDx primary testicular tumour

Testicular metastasis is a the discontiguous spread of a malignant tumour to the testis.

General

  • Rare as first presentation - case report worthy.[1][2]
  • May be the first manifestation of an abdominal malignancy.[2]

Reports:

Most common in order:[2]

  • Prostate, lung, melanoma, kidney, GI tract.

Microscopic

Features:

DDx:

Images

www

See also

References

  1. 1.0 1.1 Li, B.; Cai, H.; Kang, ZC.; Wu, H.; Hou, JG.; Ma, LY. (Jun 2015). "Testicular metastasis from gastric carcinoma: A case report.". World J Gastroenterol 21 (21): 6764-8. doi:10.3748/wjg.v21.i21.6764. PMID 26074716.
  2. 2.0 2.1 2.2 2.3 Cormio, L.; Sanguedolce, F.; Massenio, P.; Di Fino, G.; Bruno, M.; Carrieri, G. (2015). "Testicular metastasis as the first clinical manifestation of pancreatic adenocarcinoma: a case report.". J Med Case Rep 9: 139. doi:10.1186/s13256-015-0626-4. PMID 26066034.
  3. Fragkoulis, C.; Pappas, A.; Goumas, G.; Gkialas, I.; Ntoumas, K.. "Renal cell carcinoma with metastasis to the testis.". J BUON 20 (2): 663. PMID 26011366.
  4. Shinn, BJ.; Greenwald, DW.; Ahmad, N. (2015). "Unilateral testicular metastasis of low PSA level prostatic adenocarcinoma.". BMJ Case Rep 2015. doi:10.1136/bcr-2015-209914. PMID 25994435.
  5. 5.0 5.1 Buck, DA.; Byrd, RH.; Holmes, CL.; Pollock, T.. "Testicular metastasis in a case of squamous cell carcinoma of the lung.". Case Rep Oncol 8 (1): 133-7. doi:10.1159/000380814. PMID 25873879.