Difference between revisions of "TFE3"

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m (other tumours)
Line 24: Line 24:
*[[Xp11.2 translocation carcinoma]].
*[[Xp11.2 translocation carcinoma]].
*[[Alveolar soft part sarcoma]].
*[[Alveolar soft part sarcoma]].
* YAP-TFE3 translocated [[epithelioid hemangioendothelioma]]
*[[Epithelioid angiomyolipoma]]
*[[Granular cell tumor]]<ref>{{cite journal |vauthors=Chamberlain BK, McClain CM, Gonzalez RS, Coffin CM, Cates JM |title=Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study |journal=Hum. Pathol. |volume=45 |issue=5 |pages=1039–44 |date=May 2014 |pmid=24746209 |doi=10.1016/j.humpath.2013.12.021 |url=}}</ref>


==See also==
==See also==

Revision as of 21:27, 6 February 2020

TFE3
Immunostain in short
Use screen to detect TFE3 rearrangements
Subspeciality urologic pathology, soft tissue pathology
Normal staining pattern nuclear stain
Positive Xp11.2 translocation carcinoma, alveolar soft part sarcoma
Negative normal tissues

TFE3 is an immunostain used in uropathology and soft tissue pathology.

Negative

  • Normal tissue.[1]
    • Staining in normal tissue described as "extremely rare" - negative in adrenal gland, breast, colon, gallbaldder, lymph node, liver, prostate and skin.[2]

Positive

See also

References

  1. URL: http://www.ihcworld.com/_newsletter/2003/focus_jul_2003.pdf. Accessed on: September 11, 2017.
  2. Argani, P.; Lal, P.; Hutchinson, B.; Lui, MY.; Reuter, VE.; Ladanyi, M. (Jun 2003). "Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions: a sensitive and specific immunohistochemical assay.". Am J Surg Pathol 27 (6): 750-61. PMID 12766578.
  3. "Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study". Hum. Pathol. 45 (5): 1039–44. May 2014. doi:10.1016/j.humpath.2013.12.021. PMID 24746209.