Splendore-Hoeppli phenomenon

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Suppurative lymphadenitis in the neck caused by Actinomyces infection. The eosinophilc rim represents the Splendore-Hoeppli phenomenon.

The Splendore-Hoeppli phenomenon is the presence of deeply eosinophilic material, typically surrounding microorganisms.[1] It it thought to be composed of immunoglobulin and necrotic debris rich in microbial antigen.


See also