Small round cell tumours
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Small round cell tumours (SRCT), also small round blue cell tumours (SRBCT), are a group of tumours that have a similar histologic appearance.
It is a group of tumours that is seen more often in childhood than adulthood.
DDx
- Neuroblastoma.
- Wilm's tumour.
- Alveolar rhabdomyosarcoma.
- Ewing sarcoma/PNET - this entity is dealt with in the bone article.
- Lymphoma (diffuse large B cell lymphoma).
- Retinoblastoma.
- Hepatoblastoma.
- Desmoplastic small round cell tumour.
Microscopic
Features:
- Sheets of cells, very cellular.
- Small cells ~ 2X RBC diameter.
- Scant cytoplasm.
- Coarse chromatin.
- Nucleolus (???).
- +/-Vascular.