Small cell carcinoma of the urinary bladder

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Small cell carcinoma of the urinary bladder
Diagnosis in short

Small cell carcinoma of the urinary bladder. H&E stain.
LM DDx small cell carcinoma of the prostate gland, lymphoma (large cell), other small round blue cell tumours
Stains pankeratin +ve, chromogranin +ve, synaptophysin +ve, CD56 +ve
Site urinary bladder
Symptoms +/-hematuria
Prevalence very rare
Prognosis poor
Clin. DDx other bladder tumours esp. urothelial carcinoma

Small cell carcinoma of the urinary bladder, abbreviated SCCUB, is a rare malignant neoplasm of the urinary bladder.

General

  • Very rare.[1]
  • Poor prognosis.[1]

Microscopic

Features:

DDx:

IHC

  • Pankeratin +ve,
  • Chromogranin +ve.
  • Synaptophysin +ve.
  • CD56 +ve.

Images

  • SmCC bladder - intermed. mag.

  • SmCC bladder - high mag.

  • SmCC bladder - very high mag.

See also

References

  1. ↑ 1.0 1.1 Koga, F.; Yokoyama, M.; Fukushima, H. (Nov 2013). "Small cell carcinoma of the urinary bladder: a contemporary review with a special focus on bladder-sparing treatments.". Expert Rev Anticancer Ther 13 (11): 1269-79. doi:10.1586/14737140.2013.851605. PMID 24168010.
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