Difference between revisions of "Small cell carcinoma"

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'''Small cell carcinoma''' is a type of carcinoma.  It is mostly commonly from the [[lung tumours|lung]] ~95% of cases.<ref name=pmid21618245/>
'''Small cell carcinoma''' is a type of carcinoma.  It is mostly commonly from the [[lung tumours|lung]] ~95% of cases.<ref name=pmid21618245/>


==Sites other than lung==
==Overview==
*Breast.<ref name=pmid21657157>{{Cite journal  | last1 = Cesaretti | first1 = M. | last2 = Guarnieri | first2 = A. | last3 = Gaggelli | first3 = I. | last4 = Tirone | first4 = A. | last5 = Francioli | first5 = N. | last6 = Carli | first6 = AF. | title = Small cell carcinoma of the breast. Report of a case. | journal = Ann Ital Chir | volume = 82 | issue = 1 | pages = 61-4 | month =  | year =  | doi =  | PMID = 21657157 }}</ref>
===Grouping===
*Thyroid gland.<ref name=pmid21644012>{{Cite journal  | last1 = Beach | first1 = DF. | last2 = Klump | first2 = WJ. | last3 = Haddad | first3 = G. | last4 = Reid | first4 = LM. | last5 = Schwarting | first5 = R. | last6 = Hageboutros | first6 = A. | title = Extrapulmonary small cell: a novel case of small cell carcinoma of the thyroid gland. | journal = Med Oncol | volume =  | issue =  | pages =  | month = Jun | year = 2011 | doi = 10.1007/s12032-011-9996-7 | PMID = 21644012 }}</ref>
 
==Grouping==
May be grouped as:<ref name=pmid21618245>{{Cite journal  | last1 = Grossman | first1 = RA. | last2 = Pedroso | first2 = FE. | last3 = Byrne | first3 = MM. | last4 = Koniaris | first4 = LG. | last5 = Misra | first5 = S. | title = Does surgery or radiation therapy impact survival for patients with extrapulmonary small cell cancers? | journal = J Surg Oncol | volume =  | issue =  | pages =  | month = May | year = 2011 | doi = 10.1002/jso.21976 | PMID = 21618245 }}</ref>
May be grouped as:<ref name=pmid21618245>{{Cite journal  | last1 = Grossman | first1 = RA. | last2 = Pedroso | first2 = FE. | last3 = Byrne | first3 = MM. | last4 = Koniaris | first4 = LG. | last5 = Misra | first5 = S. | title = Does surgery or radiation therapy impact survival for patients with extrapulmonary small cell cancers? | journal = J Surg Oncol | volume =  | issue =  | pages =  | month = May | year = 2011 | doi = 10.1002/jso.21976 | PMID = 21618245 }}</ref>
*[[Lung|Pulmonary]].
*[[Lung|Pulmonary]].
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*Other.
*Other.


==DDx==
===Sites other than lung===
*Breast.<ref name=pmid21657157>{{Cite journal  | last1 = Cesaretti | first1 = M. | last2 = Guarnieri | first2 = A. | last3 = Gaggelli | first3 = I. | last4 = Tirone | first4 = A. | last5 = Francioli | first5 = N. | last6 = Carli | first6 = AF. | title = Small cell carcinoma of the breast. Report of a case. | journal = Ann Ital Chir | volume = 82 | issue = 1 | pages = 61-4 | month =  | year =  | doi =  | PMID = 21657157 }}</ref>
*Thyroid gland.<ref name=pmid21644012>{{Cite journal  | last1 = Beach | first1 = DF. | last2 = Klump | first2 = WJ. | last3 = Haddad | first3 = G. | last4 = Reid | first4 = LM. | last5 = Schwarting | first5 = R. | last6 = Hageboutros | first6 = A. | title = Extrapulmonary small cell: a novel case of small cell carcinoma of the thyroid gland. | journal = Med Oncol | volume =  | issue =  | pages =  | month = Jun | year = 2011 | doi = 10.1007/s12032-011-9996-7 | PMID = 21644012 }}</ref>
 
==Microscopic==
Features:
*Small cells -- typically 15-20 micrometers ~ 2x the size of [[RBC]].
*Scant cytoplasm.
*Stippled chromatin.
*+/-Nuclear moulding.
 
Images:
*[http://commons.wikimedia.org/wiki/File:Small_cell_lung_cancer_-_cytology.jpg Small cell carcinoma - cytology (WC)].
*[http://commons.wikimedia.org/wiki/File:Metastatic_small_cell_carcinoma_-_high_mag.jpg Metastatic small cell carcinoma - high mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Metastatic_small_cell_carcinoma_-_very_high_mag.jpg Metastatic small cell carcinoma - very high mag. (WC)].
 
DDx:
*[[Small round cell tumours]].
*[[Small round cell tumours]].
*[[Chloroma]].
*[[Chloroma]].

Revision as of 16:23, 24 July 2011

Small cell carcinoma is a type of carcinoma. It is mostly commonly from the lung ~95% of cases.[1]

Overview

Grouping

May be grouped as:[1]

Sites other than lung

Microscopic

Features:

  • Small cells -- typically 15-20 micrometers ~ 2x the size of RBC.
  • Scant cytoplasm.
  • Stippled chromatin.
  • +/-Nuclear moulding.

Images:

DDx:

See also

References

  1. 1.0 1.1 Grossman, RA.; Pedroso, FE.; Byrne, MM.; Koniaris, LG.; Misra, S. (May 2011). "Does surgery or radiation therapy impact survival for patients with extrapulmonary small cell cancers?". J Surg Oncol. doi:10.1002/jso.21976. PMID 21618245.
  2. Cesaretti, M.; Guarnieri, A.; Gaggelli, I.; Tirone, A.; Francioli, N.; Carli, AF.. "Small cell carcinoma of the breast. Report of a case.". Ann Ital Chir 82 (1): 61-4. PMID 21657157.
  3. Beach, DF.; Klump, WJ.; Haddad, G.; Reid, LM.; Schwarting, R.; Hageboutros, A. (Jun 2011). "Extrapulmonary small cell: a novel case of small cell carcinoma of the thyroid gland.". Med Oncol. doi:10.1007/s12032-011-9996-7. PMID 21644012.