Sinusitis

Sinusitis is a thing that occasionally comes to the pathologist. This article deals with nonspecific sinusitis, i.e. sinusitis without an identifiable cause.

General

• Clinical diagnosis.
• Benign.
• Very common in general.

Microscopic

Features:

• Sinonasal mucosa.
  • Ciliated epithelium.
  • +/-Squamous epithelium.
  • Subepithelial glands.
• Inflammatory cells.
  • Plasma cells - usu. predominant.
  • Lymphocytes.
• +/-Bone.

DDx:

• Nasal polyps.

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MIDDLE TURBINATE, LEFT, EXCISION:
- INFLAMED SINONASAL MUCOSA AND BONE.
- NEGATIVE FOR MALIGNANCY.

LEFT SINUS TISSUE, EXCISION:
- SINONASAL MUCOSA WITH CHRONIC INFLAMMATORY CELLS (PREDOMINANTLY LYMPHOCYTES AND
  PLASMA CELLS).
- NEGATIVE FOR MALIGNANCY.

Micro

The sections show mucosa with a ciliated epithelium and bland subepithelial glands. Abundant inflammatory cells, predominantly plasma cells and lymphocytes, are present. There is a lesser amount of neutrophils. Eosinophils are not significant component of the inflammation. There is no significant nuclear atypia. Mitotic activity is not readily apparent. Benign bone is present.

See also

• Head and neck pathology.