Silicone granuloma

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Silicone granuloma is a foreign body granuloma elicited by silicone, which has been used in breast implants.

General

  • Presence is used as a basis for litigation.[1]

Microscopic

Features:

  • Foreign body-type granulomas with giant cells.
  • Translucent foreign material - seen with polarized light.

Images:

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Breast Nodule, Right Lateral, Excision:
     - Consistent with siliconoma; benign fibradipose tissue with 
       inflammation, and foreign body granulomas.
     - NEGATIVE for definite breast parenchyma.
     - NEGATIVE for evidence of malignancy.

See also

References

  1. Austad, ED. (Apr 2002). "Breast implant-related silicone granulomas: the literature and the litigation.". Plast Reconstr Surg 109 (5): 1724-30; discussion 1731-2. PMID 11932626.
  2. URL: http://granuloma.homestead.com/granuloma_foreignbody.html. Accessed on: 22 January 2012.
  3. URL: http://dermatology-s10.cdlib.org/147/letter/silicone/ricotti.html. Accessed on: 22 January 2012.