Difference between revisions of "Proton pump inhibitor effect"

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==See also==
==See also==
*[[Stomach]].
*[[Stomach]].
*[[Glycogenic acanthosis of the esophagus]].


==References==
==References==

Revision as of 10:18, 16 May 2015

Stomach with PPI effect. H&E stain.

Proton pump inhibitor effect, abbreviated PPI effect, is a change seen in the parietal cells of the stomach due to a drug in the proton pump inhibitor class.

Formally, it is stomach with proton pump inhibitor effect.

General

Some proton pump inhibitors

Generic name Brand name(s)
Omeprazole LOSEC
Dexlansoprazole DEXILANT
Lansoprazole PREVACID
Esomeprazole NEXIUM
Pantoprazole PANTOLOC
Rabeprazole PARIET

Microscopic

Features:[1]

  • Parietal cell enlargement - key feature.
    • Parietal cells typically bulge into the lumen.

Images

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  • Usually not reported.

See also

References

  1. Driman, DK.; Wright, C.; Tougas, G.; Riddell, RH. (Oct 1996). "Omeprazole produces parietal cell hypertrophy and hyperplasia in humans.". Dig Dis Sci 41 (10): 2039-47. PMID 8888719.