Difference between revisions of "Proton pump inhibitor effect"

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[[Image:Stomach with PPI effect -- very high mag.jpg|thumb|right|250px|Stomach with PPI effect. [[H&E stain]].]]
[[Image:Stomach with prominent parietal cells -- very high mag.jpg|thumb|right|250px|Stomach with PPI effect. [[H&E stain]].]]
'''Proton pump inhibitor effect''', abbreviated '''PPI effect''', is a change seen in the parietal cells of the [[stomach]] due to a drug in the proton pump inhibitor class.
'''Proton pump inhibitor effect''', abbreviated '''PPI effect''', is a change seen in the parietal cells of the [[stomach]] due to a drug in the proton pump inhibitor class.


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===Images===
===Images===
<gallery>
<gallery>
Image: Stomach with PPI effect -- intermed mag.jpg | PPI effect - intermed. mag. (WC)
Image: Stomach with prominent parietal cells -- intermed mag.jpg | PPI effect - intermed. mag.
Image: Stomach with PPI effect -- high mag.jpg | PPI effect - high mag. (WC)
Image: Stomach with prominent parietal cells -- high mag.jpg | PPI effect - high mag.
Image: Stomach with PPI effect -- very high mag.jpg | PPI effect - very high mag. (WC)
Image: Stomach with prominent parietal cells -- very high mag.jpg | PPI effect - very high mag.
</gallery>
</gallery>
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Revision as of 00:11, 18 January 2014

Stomach with PPI effect. H&E stain.

Proton pump inhibitor effect, abbreviated PPI effect, is a change seen in the parietal cells of the stomach due to a drug in the proton pump inhibitor class.

Formally, it is stomach with proton pump inhibitor effect.

General

Microscopic

Features:[1]

  • Parietal cell enlargement - key feature.
    • Parietal cells typically bulge into the lumen.

Images

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  • Usually not reported.

See also

References

  1. Driman, DK.; Wright, C.; Tougas, G.; Riddell, RH. (Oct 1996). "Omeprazole produces parietal cell hypertrophy and hyperplasia in humans.". Dig Dis Sci 41 (10): 2039-47. PMID 8888719.