Difference between revisions of "Progesterone receptor"

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{{ Infobox immunostain
{{ Infobox immunostain
| Name      = {{PAGENAME}}
| Name      = {{PAGENAME}}
| Image      =  
| Image      = Pulmonary meningothelial-like nodule - PR -- high mag.jpg
| Width      =
| Width      =
| Caption    = PgR+ve in metastatic breast carcinoma.
| Caption    = PR staining in [[pulmonary meningothelial-like nodule]].
| Abbrev    = PgR
| Abbrev    = PgR
| Synonyms  =
| Synonyms  =
Line 11: Line 11:
| Subspecial =   
| Subspecial =   
| Pattern    = nuclear staining
| Pattern    = nuclear staining
| Positive  = Breast carcinoma
| Positive  = many breast carcinomas, [[pulmonary meningothelial-like nodule]]
| Negative  =  
| Negative  =  
| Other      =
| Other      =
}}
}}
'''Progesterone receptor''', abbreviated '''PgR''', is a common [[immunostain]].
'''Progesterone receptor''', abbreviated '''PgR''', is a common [[immunostain]].


==General==
==General==
*Nuclear stain.
*Nuclear stain.


==Positive==
==Positive==
Line 26: Line 24:
**Neuroendocrine carcinoma of the breast.<ref>{{Cite journal  | last1 = Lavigne | first1 = M. | last2 = Menet | first2 = E. | last3 = Tille | first3 = JC. | last4 = Lae | first4 = M. | last5 = Fuhrmann | first5 = L. | last6 = Bonneau | first6 = C. | last7 = Deniziaut | first7 = G. | last8 = Melaabi | first8 = S. | last9 = Ng | first9 = CCK. | title = Comprehensive clinical and molecular analyses of neuroendocrine carcinomas of the breast. | journal = Mod Pathol | volume = 31 | issue = 1 | pages = 68-82 | month = Jan | year = 2018 | doi = 10.1038/modpathol.2017.107 | PMID = 28884749 }}</ref>
**Neuroendocrine carcinoma of the breast.<ref>{{Cite journal  | last1 = Lavigne | first1 = M. | last2 = Menet | first2 = E. | last3 = Tille | first3 = JC. | last4 = Lae | first4 = M. | last5 = Fuhrmann | first5 = L. | last6 = Bonneau | first6 = C. | last7 = Deniziaut | first7 = G. | last8 = Melaabi | first8 = S. | last9 = Ng | first9 = CCK. | title = Comprehensive clinical and molecular analyses of neuroendocrine carcinomas of the breast. | journal = Mod Pathol | volume = 31 | issue = 1 | pages = 68-82 | month = Jan | year = 2018 | doi = 10.1038/modpathol.2017.107 | PMID = 28884749 }}</ref>
*[[Meningioma]] - most except for fibromatous subtype.<ref>{{Cite journal  | last1 = Schnegg | first1 = JF. | last2 = Gomez | first2 = F. | last3 = LeMarchand-Beraud | first3 = T. | last4 = de Tribolet | first4 = N. | title = Presence of sex steroid hormone receptors in meningioma tissue. | journal = Surg Neurol | volume = 15 | issue = 6 | pages = 415-8 | month = Jun | year = 1981 | doi =  | PMID = 7280951 }}</ref><ref>{{Cite journal  | last1 = Tilzer | first1 = LL. | last2 = Plapp | first2 = FV. | last3 = Evans | first3 = JP. | last4 = Stone | first4 = D. | last5 = Alward | first5 = K. | title = Steroid receptor proteins in human meningiomas. | journal = Cancer | volume = 49 | issue = 4 | pages = 633-6 | month = Feb | year = 1982 | doi =  | PMID = 7055777 }}</ref>
*[[Meningioma]] - most except for fibromatous subtype.<ref>{{Cite journal  | last1 = Schnegg | first1 = JF. | last2 = Gomez | first2 = F. | last3 = LeMarchand-Beraud | first3 = T. | last4 = de Tribolet | first4 = N. | title = Presence of sex steroid hormone receptors in meningioma tissue. | journal = Surg Neurol | volume = 15 | issue = 6 | pages = 415-8 | month = Jun | year = 1981 | doi =  | PMID = 7280951 }}</ref><ref>{{Cite journal  | last1 = Tilzer | first1 = LL. | last2 = Plapp | first2 = FV. | last3 = Evans | first3 = JP. | last4 = Stone | first4 = D. | last5 = Alward | first5 = K. | title = Steroid receptor proteins in human meningiomas. | journal = Cancer | volume = 49 | issue = 4 | pages = 633-6 | month = Feb | year = 1982 | doi =  | PMID = 7055777 }}</ref>
*[[Pulmonary meningothelial-like nodule]].


===Occasionally positive===
===Occasionally positive===

Revision as of 18:50, 18 April 2019

Progesterone receptor
Immunostain in short

PR staining in pulmonary meningothelial-like nodule.
Abbreviation PgR
Normal staining pattern nuclear staining
Positive many breast carcinomas, pulmonary meningothelial-like nodule

Progesterone receptor, abbreviated PgR, is a common immunostain.

General

  • Nuclear stain.

Positive

Occasionally positive

Lung adenocarcinoma.[4]

Negative

See also

References

  1. Lavigne, M.; Menet, E.; Tille, JC.; Lae, M.; Fuhrmann, L.; Bonneau, C.; Deniziaut, G.; Melaabi, S. et al. (Jan 2018). "Comprehensive clinical and molecular analyses of neuroendocrine carcinomas of the breast.". Mod Pathol 31 (1): 68-82. doi:10.1038/modpathol.2017.107. PMID 28884749.
  2. Schnegg, JF.; Gomez, F.; LeMarchand-Beraud, T.; de Tribolet, N. (Jun 1981). "Presence of sex steroid hormone receptors in meningioma tissue.". Surg Neurol 15 (6): 415-8. PMID 7280951.
  3. Tilzer, LL.; Plapp, FV.; Evans, JP.; Stone, D.; Alward, K. (Feb 1982). "Steroid receptor proteins in human meningiomas.". Cancer 49 (4): 633-6. PMID 7055777.
  4. Berardi, R.; Morgese, F.; Santinelli, A.; Onofri, A.; Biscotti, T.; Brunelli, A.; Caramanti, M.; Savini, A. et al. (Dec 2016). "Hormonal receptors in lung adenocarcinoma: expression and difference in outcome by sex.". Oncotarget 7 (50): 82648-82657. doi:10.18632/oncotarget.12244. PMID 27690341.