Polyomavirus nephropathy
Jump to navigation
Jump to search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
Polyomavirus nephropathy is a pathology seen in renal transplants.
General
- This pathology is associated with failure of transplanted kidneys.[1]
- Treatment: reduce immunosuppression.[2]
- Implicated in urothelial carcinoma - esp. in renal transplant recipients.[3]
Microscopic
Features:[2]
- Ground glass-like nuclear inclusions.
- Nuclear enlargement.
Images
PN - high mag. (WC)
PN - very high mag. (WC)
www:
IHC
Features:
Images
PN - high mag. (WC/Nephron)
PN - very high mag. (WC/Nephron)
www:
See also
References
- ↑ Mackenzie EF, Poulding JM, Harrison PR, Amer B (1978). "Human polyoma virus (HPV)--a significant pathogen in renal transplantation". Proc Eur Dial Transplant Assoc 15: 352–60. PMID 216990.
- ↑ 2.0 2.1 Nickeleit, Volker; Singh, Harsharan K. Polyomavirus Allograft Nephropathy: Clinico-Pathological Correlations. URL: http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A74503#A74539. Accessed on: 8 November 2010.
- ↑ Roberts, IS.; Besarani, D.; Mason, P.; Turner, G.; Friend, PJ.; Newton, R. (Nov 2008). "Polyoma virus infection and urothelial carcinoma of the bladder following renal transplantation.". Br J Cancer 99 (9): 1383-6. doi:10.1038/sj.bjc.6604711. PMID 18971934.
- ↑ URL: http://tpis1.upmc.com:81/tpis/kidney/KAINbk.html. Accessed on: 11 November 2011.
- ↑ Lautenschlager, I.; Jahnukainen, T.; Kardas, P.; Lohi, J.; Auvinen, E.; Mannonen, L.; Dumoulin, A.; Hirsch, HH. et al. (Dec 2014). "A case of primary JC polyomavirus infection-associated nephropathy.". Am J Transplant 14 (12): 2887-92. doi:10.1111/ajt.12945. PMID 25359127.