Pneumonia

From Libre Pathology
Revision as of 06:30, 28 December 2011 by Michael (talk | contribs) (more)
Jump to navigation Jump to search

Pneumonia is inflammation of the lung and grouped with the medical lung diseases.

There are various types of pneumonia.

Infectious pnemonia

Anatomical classification of pneumonia

  • Generally, not used by clinicians.
  • Use of the terms without qualification is discouraged... as they do not make explicit the etiology.

Bronchopneumonia

  • Multiple foci of (acute) inflammation involving the bronchi.
  • This is the most common form of (infectious) pneumonia.

Lobular pneumonia

  • Pneumonia that involves a hole lobe.
  • Rarely seen in areas where antibiotic treatments are widely available.

Acute infectious pneumonia

General

  • This is seen by pathologists, in autopsy, from time-to-time.

Most common cause:

  • Streptococcus pneumoniae.[1]

The top three community acquired (acute) pneumonia:[2]

  • Streptococcuc pneumonia.
  • Haemophilus influenzae.
  • Moraxella catarrhalis.

Other community acquired pneumonia:[1]

  • S. aureus.
  • Legionaella pneumophila.
  • Klebsiella pneumoniae.
  • Pseudomonas.

Hospital-acquired pneumonia:[1]

  • Gram-negative rods.
  • Staphylococcus aureus.

Radiologic correlate

  • Air space disease.

Gross pathology

  • Consolidation (the lung parenchyma is firm) - best appreciated by running a finger over the cut surface of the lung with a small-to-moderate amount of pressure.

Microscopic

Features:

  • Alveoli packed with PMNs.
  • +/-Clusters of bacteria - small dots or rods.

Image: Normal alveoli & pneumonia (WC).

Stains

  • Gram stain -- to type the bacteria.

Chronic infectious pneumonia

General

Common microorganisms:[1]

Note:

  • All of the later ones are granulomatous.

Microscopic

Features:

Diffuse lung diseases

  • AKA idiopathic interstitial pneumonia.

Histologic pattern:

See also

References

  1. 1.0 1.1 1.2 1.3 Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon (2009). Robbins and Cotran pathologic basis of disease (8th ed.). Elsevier Saunders. pp. 711. ISBN 978-1416031215.
  2. Nicolau, D. (Sep 2002). "Clinical and economic implications of antimicrobial resistance for the management of community-acquired respiratory tract infections.". J Antimicrob Chemother 50 Suppl S1: 61-70. PMID 12239229.