Peritoneal inclusion cyst
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Peritoneal inclusion cyst is a relatively uncommon benign pathology of the peritoneum.[1]
It is also known as benign multicystic mesothelioma; it should not be confused with malignant mesothelioma and benign papillary mesothelioma.
It may referred to as inflammatory cyst of the peritoneum or mesothelial inclusion cyst.[citation needed]
Multilocular peritoneal inclusion cyst redirect here.
General
- Usually conservative management.
- Serum CA-125 usually low.
- May occur in men.[2]
Gross
Features:[3]
- Multilocular thin-walled cysts containing serous fluid +/- blood.
- Occasionally unilocular.
- May be up to 15 cm.
- Can be adherent to the ovary.
Microscopic
- Thin-walled, irregular-shaped, cysts - unicystic or multicystic.
- Mesothelial lining +/- squamous metaplasia.[5]
- Eosinophilic fluid.
DDx:
- Ovarian serous borderline tumour.
- Ovarian serous carcinoma.
- Primary peritoneal serous carcinoma.
- Primary peritoneal malignant mesothelioma.
Images:
IHC
Features:[6]
- Calretinin +ve.
- WT-1 +ve.
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Greater Omentum, Excision:
- Multilocular peritoneal inclusion cyst with reactive changes.
- Adipose tissue with necrosis.
- NEGATIVE for malignancy.
See also
References
- ↑ 1.0 1.1 Vallerie, AM.; Lerner, JP.; Wright, JD.; Baxi, LV. (May 2009). "Peritoneal inclusion cysts: a review.". Obstet Gynecol Surv 64 (5): 321-34. doi:10.1097/OGX.0b013e31819f93d4. PMID 19386139.
- ↑ Cavallaro, A.; Murazio, M.; Modugno, P.; Vona, A.; Revelli, L.; Potenza, AE.; Colli, R.. "Benign multicystic mesothelioma of the peritoneum: a case report.". Chir Ital 54 (4): 569-72. PMID 12239771.
- ↑ McFadden, DE.; Clement, PB. (Dec 1986). "Peritoneal inclusion cysts with mural mesothelial proliferation. A clinicopathological analysis of six cases.". Am J Surg Pathol 10 (12): 844-54. PMID 3789251.
- ↑ Levy, AD.; Arnáiz, J.; Shaw, JC.; Sobin, LH.. "From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation.". Radiographics 28 (2): 583-607; quiz 621-2. doi:10.1148/rg.282075175. PMID 18349460.
- ↑ Ross, MJ.; Welch, WR.; Scully, RE. (Sep 1989). "Multilocular peritoneal inclusion cysts (so-called cystic mesotheliomas).". Cancer 64 (6): 1336-46. PMID 2766227.
- ↑ 6.0 6.1 Takemoto, S.; Kawano, R.; Honda, K.; Nakazono, A.; Shimamatsu, K. (2012). "Benign multicystic peritoneal mesothelioma mimicking recurrence of an ovarian borderline tumor: a case report.". J Med Case Rep 6 (1): 126. doi:10.1186/1752-1947-6-126. PMID 22583977.