Paired box gene 5
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Paired box gene 5 | |
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Immunostain in short | |
PAX5 staining in a classical Hodgkin's lymphoma | |
Abbreviation | PAX5 |
Use | B-cell marker, weakly positive in classical Hodgkin's lymphoma |
Subspeciality | hematopathology |
Normal staining pattern | nuclear stain |
Positive | B-cell lymphoma, classical Hodgkin's lymphoma |
Paired box gene 5, commonly known by the abbreviation PAX5, is a immunostain used in hematopathology.
Tumours with positive staining
- B-cell lymphomas
- Hodgkin lymphoma
- typically weak in classical Hodgkin's lymphoma
- strong in nodular lymphocyte-predominant Hodgkin's lymphoma
Negative staining
- Plasmablastic neoplasms