Difference between revisions of "Organizing pneumonia"

From Libre Pathology
Jump to navigation Jump to search
(chg redirect)
(split out)
Line 1: Line 1:
#redirect [[Diffuse_lung_diseases#Organizing_pneumonia]]
#redirect [[Diffuse_lung_diseases#Organizing_pneumonia]]
'''Organizing pneumonia''', abbreviated '''OP''', is a histologic pattern in [[lung pathology]].
==General==
*Multiple causes, e.g. transplant rejection, infection.
Clinical diagnoses:<ref name=Ref_WMSP91>{{Ref WMSP|91}}</ref>
*[[Lung transplant pathology|Transplant rejection]].
*Cryptogenic organizing pneumonia (COP), [[AKA]] (idiopathic) bronchiolitis obliterans organizing pneumonia (BOOP).
**Should '''not''' be confused with ''[[constrictive bronchiolitis]]'' (AKA ''[[bronchiolitis obliterans]]'').
*[[Collagen vascular disease]].
*Toxic injury.
*Infection.
*Peri-tumor - in proximity to a space-occupying lesion (abscess, neoplasm).
Note:
*BOOP is used as a synonym for ''organizing pneumonia'' which has the long differential diagnosis above.<ref name=Ref_WMSP91>{{Ref WMSP|91}}</ref>
**Confusingly, it may be used to refer to the idiopathic form of organizing pneumonia, now generally known as ''cryptogenic organizing pneumonia'' (COP).
***In other words, strictly speaking, ''BOOP'' is '''not''' the same as ''COP''; idiopathic BOOP ''is'' COP.
==Microscopic==
Features:<ref name=Ref_Klatt110>{{Ref Klatt|110}}</ref>
*Distal airway disease -- airways plugged with organizing exudate ("[[Masson bodies]]").
**"Organized exudate" = fluffy light-staining paucicellular regions with stellate cells (fibroblasts & immature connective tissue).
*'''No''' hobnailing of pneumocytes.
**Type 2 pneumocytes hyperplasia is absent.
DDx:
*[[Diffuse alveolar damage]], proliferative phase - has type 2 pneumoncyte hyperplasia.
*[[Bronchiolitis obliterans]].
===Images===
<gallery>
Image:Masson_body_-_intermed_mag.jpg | Masson body - intermed. mag. (WC/Nephron)
Image:Masson_body_-_very_high_mag.jpg | Masson body - very high mag. (WC/Nephron)
</gallery>
www:
*[http://150.59.224.157/pathology/system/data/image_data/11338411170518.jpg Masson body (150.59.224.157)].<ref>URL: [http://150.59.224.157/pathology/index.php?first_category_id=2&second_category_id=20 http://150.59.224.157/pathology/index.php?first_category_id=2&second_category_id=20]. Accessed on: 4 August 2011.</ref>
*[http://casereports.bmj.com/content/2011/bcr.11.2010.3483.full BOOP (bmj.com)].
*[http://www.flickr.com/photos/pulmonary_pathology/4733384977/ Masson body (flickr.com)].
==See also==
*[[Diffuse lung disease]].
*[[Pneumonia]].
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Diffuse lung diseases]]

Revision as of 01:58, 31 May 2014

Redirect to:

Organizing pneumonia, abbreviated OP, is a histologic pattern in lung pathology.

General

  • Multiple causes, e.g. transplant rejection, infection.

Clinical diagnoses:[1]

Note:

  • BOOP is used as a synonym for organizing pneumonia which has the long differential diagnosis above.[1]
    • Confusingly, it may be used to refer to the idiopathic form of organizing pneumonia, now generally known as cryptogenic organizing pneumonia (COP).
      • In other words, strictly speaking, BOOP is not the same as COP; idiopathic BOOP is COP.

Microscopic

Features:[2]

  • Distal airway disease -- airways plugged with organizing exudate ("Masson bodies").
    • "Organized exudate" = fluffy light-staining paucicellular regions with stellate cells (fibroblasts & immature connective tissue).
  • No hobnailing of pneumocytes.
    • Type 2 pneumocytes hyperplasia is absent.

DDx:

Images

  • Masson body - intermed. mag. (WC/Nephron)

  • Masson body - very high mag. (WC/Nephron)

www:

See also

References

  1. ↑ 1.0 1.1 Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 91. ISBN 978-0781765275.
  2. ↑ Klatt, Edward C. (2006). Robbins and Cotran Atlas of Pathology (1st ed.). Saunders. pp. 110. ISBN 978-1416002741.
  3. ↑ URL: http://150.59.224.157/pathology/index.php?first_category_id=2&second_category_id=20. Accessed on: 4 August 2011.
Retrieved from "https://librepathology.org/w/index.php?title=Organizing_pneumonia&oldid=31813"