Difference between revisions of "Nodal nevus"

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| Other      =
 
| Other      =
 
| ClinDDx    = [[lymph node metastasis]]
 
| ClinDDx    = [[lymph node metastasis]]
| Tx        = none
+
| Tx        = none or follow-up
 
}}
 
}}
 
'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] finding that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal  | last1 = Lee | first1 = JJ. | last2 = Granter | first2 = SR. | last3 = Laga | first3 = AC. | last4 = Saavedra | first4 = AP. | last5 = Zhan | first5 = Q. | last6 = Guo | first6 = W. | last7 = Xu | first7 = S. | last8 = Murphy | first8 = GF. | last9 = Lian | first9 = CG. | title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. | journal = Mod Pathol | volume = 28 | issue = 2 | pages = 218-29 | month = Feb | year = 2015 | doi = 10.1038/modpathol.2014.99 | PMID = 25081754 }}</ref>
 
'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] finding that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal  | last1 = Lee | first1 = JJ. | last2 = Granter | first2 = SR. | last3 = Laga | first3 = AC. | last4 = Saavedra | first4 = AP. | last5 = Zhan | first5 = Q. | last6 = Guo | first6 = W. | last7 = Xu | first7 = S. | last8 = Murphy | first8 = GF. | last9 = Lian | first9 = CG. | title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. | journal = Mod Pathol | volume = 28 | issue = 2 | pages = 218-29 | month = Feb | year = 2015 | doi = 10.1038/modpathol.2014.99 | PMID = 25081754 }}</ref>
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==General==
 
==General==
 
*[[Lymph node metastases]] from cutaneous melanoma are common and seen in approximately 20% of cases.<ref name=pmid28802493>{{Cite journal  | last1 = Prieto | first1 = VG. | title = Sentinel Lymph Nodes in Cutaneous Melanoma. | journal = Clin Lab Med | volume = 37 | issue = 3 | pages = 417-430 | month = 09 | year = 2017 | doi = 10.1016/j.cll.2017.05.002 | PMID = 28802493 }}</ref>
 
*[[Lymph node metastases]] from cutaneous melanoma are common and seen in approximately 20% of cases.<ref name=pmid28802493>{{Cite journal  | last1 = Prieto | first1 = VG. | title = Sentinel Lymph Nodes in Cutaneous Melanoma. | journal = Clin Lab Med | volume = 37 | issue = 3 | pages = 417-430 | month = 09 | year = 2017 | doi = 10.1016/j.cll.2017.05.002 | PMID = 28802493 }}</ref>
*May be confused with [[malignant melanoma]].<ref name=pmid27810606>{{Cite journal  | last1 = Davis | first1 = J. | last2 = Patil | first2 = J. | last3 = Aydin | first3 = N. | last4 = Mishra | first4 = A. | last5 = Misra | first5 = S. | title = Capsular nevus versus metastatic malignant melanoma - a diagnostic dilemma. | journal = Int J Surg Case Rep | volume = 29 | issue =  | pages = 20-24 | month =  | year = 2016 | doi = 10.1016/j.ijscr.2016.10.040 | PMID = 27810606 }}</ref>
+
*Nodal nevus may be confused with [[malignant melanoma]].<ref name=pmid27810606>{{Cite journal  | last1 = Davis | first1 = J. | last2 = Patil | first2 = J. | last3 = Aydin | first3 = N. | last4 = Mishra | first4 = A. | last5 = Misra | first5 = S. | title = Capsular nevus versus metastatic malignant melanoma - a diagnostic dilemma. | journal = Int J Surg Case Rep | volume = 29 | issue =  | pages = 20-24 | month =  | year = 2016 | doi = 10.1016/j.ijscr.2016.10.040 | PMID = 27810606 }}</ref>
  
 
==Gross==
 
==Gross==

Latest revision as of 09:36, 16 October 2019

Nodal nevus
Diagnosis in short

Synonyms capsular nevus, benign nevus cells in lymph node

LM bland nevus cells (lack prominent nucleoli, nuclear pleomorphism, proliferative activity)
LM DDx malignant melanoma
IHC S-100 +ve
Gross usually not apparent
Site lymph node

Signs none
Prevalence rare
Prognosis benign
Clin. DDx lymph node metastasis
Treatment none or follow-up

Nodal nevus, also capsular nevus, is benign lymph node finding that can be mistaken for malignant melanoma.[1]

Nevus in lymph node and benign nevus cells in lymph node redirect here.

General

Gross

  • Usually not apparent.

Microscopic

Features:

  • Nevus cells with bland cytomorphology.
    • Lack size variation, nucleoli.
    • Non-proliferative.

Note:

  • No standardized criteria.[3]

DDx:

Images

IHC

Features:[3]

  • S-100 +ve.

References

  1. Lee, JJ.; Granter, SR.; Laga, AC.; Saavedra, AP.; Zhan, Q.; Guo, W.; Xu, S.; Murphy, GF. et al. (Feb 2015). "5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies.". Mod Pathol 28 (2): 218-29. doi:10.1038/modpathol.2014.99. PMID 25081754.
  2. Prieto, VG. (09 2017). "Sentinel Lymph Nodes in Cutaneous Melanoma.". Clin Lab Med 37 (3): 417-430. doi:10.1016/j.cll.2017.05.002. PMID 28802493.
  3. 3.0 3.1 3.2 Davis, J.; Patil, J.; Aydin, N.; Mishra, A.; Misra, S. (2016). "Capsular nevus versus metastatic malignant melanoma - a diagnostic dilemma.". Int J Surg Case Rep 29: 20-24. doi:10.1016/j.ijscr.2016.10.040. PMID 27810606.