Nevus sebaceous

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Nevus sebaceous, also nevus sebaceous of Jadassohn, is an uncommon congenital benign skin condition.

General

  • Congenital - considered a hamartoma.[1]
  • Usually sporadic - may be transmitted autosomal dominant.[1]
  • Malignant tumours may arise within a nevus sebaceous.

Gross

Features:[1][2]

  • Head and neck plaque or papule with:
    • Well-circumscribed borders.
    • Waxy, yellow appearance.
  • Area usu. devoid of hair.[3]

DDx - gross:

Image:

Microscopic

Features:[2]

  • Abundant sebaceous glands.
  • Immature/abortive hair follicles.
    • No normal terminal hair follicles.
  • Papillomatous epidermal hyperplasia.

Images

www:

See also

References

  1. 1.0 1.1 1.2 West, C.; Narahari, S.; Kwatra, S.; Feldman, S. (Nov 2012). "Autosomal dominant transmission of nevus sebaceous of Jadassohn.". Dermatol Online J 18 (11): 17. PMID 23217958.
  2. 2.0 2.1 Simi, CM.; Rajalakshmi, T.; Correa, M.. "Clinicopathologic analysis of 21 cases of nevus sebaceus: a retrospective study.". Indian J Dermatol Venereol Leprol 74 (6): 625-7. PMID 19171988.
  3. Kim, JH.; Park, HY.; Ahn, SK. (Oct 2011). "Nevus sebaceous accompanying secondary neoplasms and unique histopathologic findings.". Ann Dermatol 23 (Suppl 2): S231-4. doi:10.5021/ad.2011.23.S2.S231. PMID 22148058.