Difference between revisions of "Neuromuscular pathology"

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Parasitic disease classically associated with consumption of uncooked pork.
Parasitic disease classically associated with consumption of uncooked pork.


=Nerve stuff=
=Nerve stuff=
=Nerve stuff=
===General===
===General===
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** Usu 6-15 fascicles in sural nerve.
** Usu 6-15 fascicles in sural nerve.
*Nerve fibre (surrounded by endoneurium).
*Nerve fibre (surrounded by endoneurium).
**Myelinated axons.
**Unmyelinated axons and their Schwann cells together are called Remak bundles.


Epineurium:
Epineurium:
** Capillaries, arterioles and venules.
* Capillaries, arterioles and venules.
** Fibroblasts, mast cells.
* Fibroblasts (CD34+/-ve, EMA-ve, S100-ve).
** Pacinian corpuscles (no pathological relevance).
* Macrophages (CD68+ve, CD168+ve).
* Mast cells (metachromatic granules).
* Leukocytes (usu. less than 10 CD3+ve Lymphocytes/mm²).
* Pacinian corpuscles (no pathological relevance).


Perineurium:
Perineurium:
** Fascicles may separated by perineurial septae.
* Fascicles may separated by perineurial septae.
** Occasional perineurial calcifications (no pathological relevance).
*Occasional perineurial calcifications (no pathological relevance).
*Renaut bodies (subperineurial whorled structures consisting of fibroblasts).
 
<gallery>
Image:N_renaut_body_semithin.jpg|Renaut body in a fascicle.
File:Pacinian Corpuscle (36298105211).jpg|Pacinian corpuscle.
</gallery>


===Stains===
===Stains===
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