Myeloproliferative neoplasms

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Myeloproliferative neoplasms, also myeloproliferative disorders are a group of indolent hematologic neoplasms.

Grouping

They include the following:[1]

  • Polycythaemia vera.
  • Essential thrombocythaemia.
  • Idiopathic myelofibrosis.

Molecular

There is a common JAK2 mutation (Val617Phe) in this group of diseases.[1]

See also

References

  1. ↑ 1.0 1.1 Baxter EJ, Scott LM, Campbell PJ, et al. (2005). "Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders". Lancet 365 (9464): 1054–61. doi:10.1016/S0140-6736(05)71142-9. PMID 15781101.
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